back to 2004, vol. 10, b. 1

Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2004, vol. 10, book 1
Subject Collection: Medicine
Page: 11-14
DOI: 10.5272/jimab.2004101.11
Online date: September 9, 2004

J of IMAB 2004; 10(1):11-14
Vesela Ouzounova, J. Haralambieva, J. Jankov, D. Petrov, I. Mitov
Department of Microbiology,
Medical Faculty, Medical University, Sofia,

The aim of the study is to investigate the prevalence of C. trachomatis infection in symptomatic patients and to compare our data with similar studies made in Bulgaria. 822 patients were includet with a suggestion of possible chlamydial infection - urethritis, prostatitis, Reiter syndrome, cervicitis, salpingitis, pelvic inflammatory disease, ectopic pregnancy, infertility, etc. The samples were cell cultured on McCoy and detected in immunofluorescence with anti-lipopolysaccharide monoclonal antibody. The prevalence of C. trachomatis infection in symptomatic patients addressing the specialists was about 37% in the investigated 822 urogenital samples (568 women and 254 men). Active infection with C. trachomatis was detected in 39% of the women and in 33% of the men. Our study shows a relatively high prevalence of C. trachomatis infection in symptomatic patients; lower prevalence of the infection in comparison with other bulgarian studies, using different methods for detection. The results prove the high sensitivity and specificity of the cell-culture method for the detection of chlamydial infections and the need for screening of the symptomatic patients and their sexual partners for chlamydial infection.

Key words: C. trachomatis, immunofluerescence.

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Please cite this article as: Ouzounova V, Haralambieva J, Jankov J, Petrov D, Mitov I. Prevalence of Chlamydia trachomatis infections in symptomatic patients in Bulgaria. J of IMAB. 2004; 10(1):11-14; DOI: 10.5272/jimab.2004101.11

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