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Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312-773X (Online)
Issue: 2010, Volume 16, book 4,
DOI: 10.5272/jimab.1642010_67
Subject Collection: Oral and Dental Medicine
Page: 67 - 69
Online date: February 21, 2011
J of IMAB 2010; 16(4):67-69
CORTISOL IN SALIVA – A MARKER FOR INCREASED ANXIETY IN CHILDREN
M. Rashkova1, P. Kalchev2, R. Emilova3, L. Ribagin1, Tz. Doganova4, I. Stoeva3
1 Department of Pediatric Dentistry, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria
2 Department of Psychology, SU “Kliment Ohridski” - Sofia, Bulgaria
3 Institute of Pediatrics, Screening and Fuctional Endocrine Diagnosis Laboratory, Medical University - Sofia, Bulgaria
4 Centre for Dental Medicine - Ruse, Bulgaria
ABSTRACT:
Objectives: Cortisol, called also “stress hormone” participates in organism’s response to stress situations and enters into complex interactions with the hormonal and immune system of a man. The purpose of the study is to follow the cortisol level in saliva as dependent on the anxiety rate in children.
Methods: A screening investigation of 170 children was carried out to evaluate anxiety rate with the help of the revised children’s manifest anxiety scale. 71 children (41 with high and 30 with low anxiety rate) were selected to measure the cortisol in the saliva by ELISA method with Saliva Cortisol Enzyme Immunoassay Kit, product of Salimetrics, USA.
Results: The results show a dependence between the subjective psychological test for anxiety evaluation in infant age and the cortisol in saliva. Saliva is used as a non-invasive diagnostic indicator for the changes in cortisol levels.
Conclusion: Cortisol is an objective oral biomarker that can be used for evaluation of risky oral environment and its connection to the general psychological status of children.
Page: 67-69; FULL TEXT PDF (135 KB) Abstract & References
Please include this information when citing this paper: DOI: 10.5272/jimab.1642010_67