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Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2007, vol. 13, book 1
Subject Collection: Medicine
Page: 27-30
DOI: 10.5272/jimab.2007131.25
Online date: September 10, 2007
J of IMAB 2007; 13(1):27-30
COMPARATIVE STUDY IN LEPTOSPIROSIS AND ACUTE VIRAL HEPATITIS
Galya I. Gancheva, Chrisima Tzvetanova, Penka Ilieva, Iskra Simova
Department of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine; Medical University, Pleven, Bulgaria
ABSTRACT:
Retrospectively have been studied clinical signs and routine laboratory investigations of patients with leptospirosis (n 1=94) and acute viral hepatitis (AVH) (n 2=1705). The comparison of results in two groups have revealed significant differences in the frequency of acute onset in leptospirosis and AVH with fever (respectively in 100% and 58,01%; p<0,005); pains in calf muscles (in leptospirosis in 85,11%, in AVH have not been observed); headache (resp. in 68,08 and 18,96%; p<0,005); anorexia (resp. in 64,89 and 87,36%; p<0,005); lumbar pains (in leptospirosis in 40,43%, in AVH have not been observed); clay colored stool (resp. in 6,38 and 93,60%; p<0,005); heaviness in abdomen (resp. in 3,19 and 84,38%; p<0,005); hepatic tenderness (resp. in 41,49 and 76,63%; p<0,005); conjunctival injection only in leptospirosis (86,17%). Routine laboratory investigations have been demonstrated anemia, leucocytosis, granulocytosis, increased erythrocytes sedimentation rate (ESR) and thrombocytopenia significantly often in leptospirosis than in AVH (p<0,005). The comparison of results of liver biochemical investigations have been established increased serum bilirubin in leptospirosis and AVH (resp. in 75,00 and 93,60%; p<0,05); mildly increased aminotransferases activities in leptospirosis and extremely increased in AVH (p<0,005); increased creatinkynase in leptospirosis; increased fibrinogen level in leptospirosis (av. 6,74 g/L), normal to decreased in AVH (av. 3,01 g/L) (p<0,005). Nitrogen parameters have been increased in leptospirosis with ARF.
Key words: leptospirosis, acute viral hepatitis, acute renal failure, liver biochemical parameters, creatinkynase, nitrogen parameters.
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Please cite this article as:
Gancheva GI, Tzvetanova Chr, Ilieva P, Simova I. COMPARATIVE STUDY IN LEPTOSPIROSIS AND ACUTE VIRAL HEPATITIS. J of IMAB. 2007; 13(1):27-30. doi: 10.5272/jimab.2007131.25
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