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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2024, vol. 30, issue4
Subject Area: Medicine
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DOI: 10.5272/jimab.2024304.5878
Published online: 29 November 2024
Case report
J of IMAB. 2024 Oct-Dec;30(4):5878-5881
TREATMENT WITH ZUCLOPENTHIXOL OF A WOMAN WITH PSYCHOSIS AND TUBEROUS SCLEROSIS: A CASE REPORT
Jacklin Natzkova1
, Mladen Penchev1, 2, Vessela Stoyanova1, 2,
1) Psychiatric clinic, UMHAT “Alexandrovska”, Sofia, Bulgaria.
2) Department of Psychiatry and Clinical Psychology, Medical University – Sofia, Bulgaria.
ABSTRACT:
This case is about a 20-year-old woman with tuberous sclerosis complex and psychosis admitted to the psychiatry clinic of UMHAT Aleksandrovska and treated with zuclopenthixol. She experienced paranoid delusions and verbal and physical aggression towards her mother. Because of side effects, the treatment with risperidone was changed to zuclopenthixol. We evaluated her condition with BPRS24. The score of BPRS24 in admission to the hospital was 97 points. At discharge, the score of BPRS24 was 54 points. After a month, the BPRS24 score was reduced to 39 points; two months later, it was 37.
Keywords: tuberous sclerosis complex, psychosis, zuclopenthixol,
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Please cite this article as: Natzkova J, Penchev M, Stoyanova V. Treatment with zuclopenthixol of a woman with psychosis and tuberous sclerosis: A case report. J of IMAB. 2024 Oct-Dec;30(4):5878-5881. [Crossref - 10.5272/jimab.2024304.5878]
Correspondence to: Jacklin Natzkova, Clinic of Psichiatry, UMHAT Aleksandrovska, Sofia; 1, Georgi Sofiiski Str., Sofia, Bulgaria; E-mail: jacklin.natzkova@gmail.com
REFERENCES:
1. Marcinowski F, Knipe H, Atkinson H, et al. Tuberous sclerosis. Reference article. Radiopaedia.org. 25 Feb 2024. [Crossref]
2. de Vries PJ, Whittemore VH, Leclezio L, Byars AW, Dunn D, Ess KC, et al. Tuberous sclerosis associated neuropsychiatric disorders (TAND) and the TAND Checklist. Pediatr Neurol. 2015 Jan;52(1):25-35. [PubMed ]
3. Overwater IE, Rietman AB, van Eeghen AM, de Wit MCY. Everolimus for the treatment of refractory seizures associated with tuberous sclerosis complex (TSC): current perspectives. Ther Clin Risk Manag. 2019 Jul 26;15:951-955. [PubMed]
4. Cervi F, Saletti V, Turner K, Peron A, Bulgheroni S, Taddei M, et al. The TAND checklist: a useful screening tool in children with tuberous sclerosis and neurofibromatosis type 1. Orphanet J Rare Dis. 2020 Sep 7;15(1):237. [PubMed]
5. Sehgal V, Yadav A, Ahluwalia I, Patil PS. Acute onset psychosis in a patient of tuberous sclerosis: A rare entity. Medical Science. 2023 Mar;27(133):e167ms2748. [Crossref]
6. Rahul C, Devika C, Swapnajeet S. Psychosis in a patient with tuberous sclerosis: A rare entity. Archives of Mental Health. 2023 Jan-Jun;24(1):51-53. [Crossref]
7. Rao SA, Rao MG, Rao NP, Varambally S, Gangadhar BN. Successful treatment of tuberous sclerosis with psychosis and obsessive-compulsive disorder: A case report. Psychiatry Clin Neurosci. 2015 Aug;69(8):504-5. [PusbMed]
8. AlZamil NA, Alkhalifa EA, Azzoni F. A 39-year-old man with schizophrenia and tuberous sclerosis with a delusion of being a pregnant woman-A case report. Clin Case Rep. 2018 Nov 25;7(1):152-154. [PubMed]
9. Zanello A, Berthoud L, Ventura J, Merlo MC. The Brief Psychiatric Rating Scale (version 4.0) factorial structure and its sensitivity in the treatment of outpatients with unipolar depression. Psychiatry Res. 2013 Dec 15;210(2):626-33. [PubMed]
10. de Vries PJ, Leclezio L, Gardner-Lubbe S, Krueger D, Sahin M, Sparagana S, et al. Multivariate data analysis identifies natural clusters of Tuberous Sclerosis Complex Associated Neuropsychiatric Disorders (TAND). Orphanet J Rare Dis. 2021 Oct 24;16(1):447. [PubMed]
11. Peng JH, Tu HP, Hong CH. A population-based study to estimate survival and standardized mortality of tuberous sclerosis complex (TSC) in Taiwan. Orphanet J Rare Dis. 2021 Aug 3;16(1):335. [PubMed]
Received: 29 July 2024
Published online: 29 November 2024