head JofIMAB
Journal of IMAB
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2024, vol. 30, issue3
Subject Area: Medicine
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DOI: 10.5272/jimab.2024303.5724
Published online: 02 September 2024

Original article
J of IMAB. 2024 Jul-Sep;30(3):5724-5727
THE PLACE OF ACELLULAR COLLAGEN MATRIX IN THE TREATMENT OF CARTILAGE DAMAGE OF THE KNEE JOINT
Hristo GigovORCID logoCorresponding Autoremail, Mancho KovachevORCID logo, Simeon GigovORCID logo,
Department of Orthopaedics and Traumatology, Faculty of Medicine, Medical University of Pleven; Clinic of Orthopaedics and Traumatology of G. Stranski University Hospital – Pleven, Bulgaria.

ABSTRACT:
The collagen matrix has established itself as the standard in the treatment of chondral and osteochondral injuries of the knee joint.
Purpose: The application of this surgical technique aims at the restoration and regeneration of the defect with hyaline cartilage, which is the basis for achieving good early and long-term clinical results.
Material and Methods: We present 36 patients who are surgically treated with this technique. Patients are divided into two groups according to the etiological principle.
Results: Results are defined as good and very good and are comparable to the results of other similar retrospective studies.
Conclusions: The method is applicable in selected cases of a traumatic and degenerative nature and is an alternative to early knee arthroplasty.

Keywords: collagen matrix, cartilage damage, knee joint,

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Please cite this article as: Gigov H, Kovachev M, Gigov S. The place of acellular collagen matrix in the treatment of cartilage damage of the knee joint. J of IMAB. 2024 Jul-Sep;30(3):5724-5727. [Crossref - 10.5272/jimab.2024303.5724]

Corresponding AutorCorrespondence to: Hristo Gigov, Clinic of Orthopaedics and Traumatology of G. Stranski University Hospital – Pleven; 89, Rousse Blvd., Pleven, Bulgaria; E-mail: hristogigov@yahoo.com

REFERENCES:
1. Detterline AJ, Goldberg S, Bach BR Jr, Cole BJ. Treatment options for articular cartilage defects of the knee. Ortop. Nurs. 2005 Sep-Oct;24(5):361-6. [PubMed]
2. Jiang CC, Hsieh CH, Liao CJ, Chang WH, Liao WJ, Tsai-Wu JJ, et al. Collagenase treatment of cartilaginous matrix promotes fusion of adjacent cartilage. Regen Ther. 2020 Jul 28;15:97-102. [PubMed]
3. Bath R, Eschweiler J, Betsch M, Gruber G. [Cartilage Repair of the knee joint.] [in German] Orthopade. 2017 Nov;46(11):919-927. [PubMed]
4. Gobbi A, Karnatzikos G, Kumar A. Long-term results after microfracture treatment for full-thickness knee chondral lesions in athletes. Knee Surg Sports Traumatol Arthrosc. 2014 Sep;22(9):1986-96. [PubMed]
5. Brittberg M, Gomoll HA, Canseco JA, Far J, Lind M, Hui J, et al. Cartilage repair in the degenerative ageing knee. Acta Orthop. 2016 Dec;87(sup363):26-38. [PubMed]
6. Slattery C, Kweon CY. Classifications in Brief: Outerbridge Classification of Chondral Lesions. Clin Orthop Relat Res. 2018 Oct;476(10):2101-2104. [PubMed]
7. Gotterbarm T, Breusch SJ, Schneider U, Jung M. The minipig model for experimental chondral and osteochondral defect repair in tissue engineering: retrospective analysis of 180 defects. Lab Anim. 2008 Jan;42(1):71-82. [PubMed]
8. Bentley G, Biant LC, Carrington RW, Akmal M, Goldberg A, Williams AM, et al. A prospective, randomized comparison of autologous chondrocyte implantation versus mosaicplasty for osteochondral defects in the knee. J Bone Joint Surg Br. 2003 Mar;85(2):223-30. [PubMed]
9. Dozin B, Malpeli M, Cancedda R, Bruzzi P, Calcagno S, Molfetta L, et al. Comparative evaluation of autologous chondrocyte implantation and mosaicplasty: a multicentered randomized clinical trial. Clin J Sport Med. 2005 Jul;15(4):220-6. [PubMed]
10. Gudas R, Stankevicius E, Monastyreckiene E, Pranys D, Kalesinskas RJ. Osteochondral autologous transplantation versus microfracture for the treatment of articular cartilage defects in the knee joint in athletes. Knee Surg Sports Traumatol Arthrosc. 2006 Sep;14(9):834-42. [PubMed]
11. Jørgensen AEM, Schjerling P, Krogsgaard MR, Petersen MM, Olsen J, Kjær M, et al. Collagen Growth Pattern in Human Articular Cartilage of the Knee. Cartilage. 2021 Dec;13(2_suppl):408S-418S. [PubMed]
12. Brittberg M. Autologous Chondrocyte transplantation. Clin Orthop Relat Res. 1999 Oct:(367 Suppl):S147-55. [PubMed]
13. Hangody L, Dobos J, Baló E, Pánics G, Hangody LR, Berkes I. Clinical experiences with autologous osteochondral mosaicplasty in an athletic population: a 17-year prospective multicenter study. Am J Sports Med. 2010 Jun;38(6):1125-33. [PubMed]
14. Jørgensen AEM, Agergaard J, Schjerling P, Heinemeier KM, van Hall G, Kjaer M. The regional turnover of cartilage collagen matrix in late-stage human knee osteoarthritis. Osteoarthritis Cartilage. 2022 Jun;30(6):886-895. [PubMed]
15. Hsueh MF, Önnerfjord P, Bolognesi MP, Easley ME, Kraus VB. Analysis of "old" proteins unmasks dynamic gradient of cartilage turnover in human limbs. Sci Adv. 2019 Oct 9;5(10):eaax3203. [PubMed]
16. Lahm A, Dabravolski D, Rödig J, Esser J, Erggelet C, Kasch R. Varying development of femoral and tibial subchondral bone tissue and their interaction with articular cartilage during progressing osteoarthritis. Arch Orthop Trauma Surg. 2020 Dec;140(12):1919-1930. [PubMed ]

Received: 15 May 2024
Published online: 02 September 2024

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