head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2024, vol. 30, issue1
Subject Area: Dental Medicine
DOI: 10.5272/jimab.2024301.5425
Published online: 14 March 2024

Case report
J of IMAB. 2024 Jan-Mar;30(1):5425-5428
Virna-Maria Tsitou1ORCID logoCorresponding Autoremail, Dimitrios Rallis2ORCID logo, Mariana Tsekova3, Nikolay Yanev4ORCID logo,
1) Department of Medical Microbiology, Faculty of Medicine, Medical University, Sofia, Bulgaria.
2) "El Greco private dental care" -private practise, Sofia, Bulgaria.
3) Department of Imaging and Oral Diagnostics, Faculty of Dental Medicine, Medical University, Sofia, Bulgaria.
4) Medico - Dental clinic “Yanev Medico Dent” Sofia, Bulgaria.

This case report examines the interrelationship between periodontitis and Alopecia areata (AA), an autoimmune condition, within the broader context of the impact of oral health on systemic diseases. The concept of "oral primary foci," encompassing various oral pathologies such as periodontitis, dentoalveolar abscesses, and pulpal necrosis, is highlighted as a key factor in systemic diseases and complications. The report details the case of a 50-year-old female patient with AA who exhibited significant improvement in her condition following periodontal treatment. This improvement underscores the potential systemic influence of oral health conditions, particularly periodontitis, which is characterized by a dynamic interplay between bacterial infection and the host's immune response. The presence of autoantibodies in periodontitis suggests an autoimmune component, potentially linking it to autoimmune diseases like AA. The patient's case also aligns with the epidemiological data on AA, emphasizing its complex etiology and association with various systemic conditions. The report concludes that effective management of oral health, especially periodontal diseases, is crucial in the systemic health and management of conditions such as AA. It advocates for a holistic approach in healthcare, integrating oral health as a fundamental aspect of managing systemic diseases, and calls for continued research into the mechanisms connecting oral and systemic autoimmune responses. This research is vital for developing comprehensive treatment strategies that address both oral and systemic health, thereby enhancing overall patient outcomes.

Keywords: Periodontitis, Alopecia areata, Oral-Systemic Health, Autoimmune Disease, Oral Primary Foci, Systemic Inflammation,

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Please cite this article as: Tsitou VM, Rallis D, Tsekova M, Yanev N. Allopecia areata and periodontitis: a case report. 2024 Jan-Mar;30(1):5425-5428. [Crossref - 10.5272/jimab.2024301.5425]

Corresponding AutorCorrespondence to: Head assistant prof. Dr Virna-Maria Tsitou, Department of Medical Microbiology, Faculty of Medicine, Medical University of Sofia; 2, Zdrave Str., 1431, Sofia, Bulgaria; E-mail: maria-tsitou@hotmail.co.uk

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Received: 05 January 2023
Published online: 14 March 2024

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