head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2024, vol. 30, issue1
Subject Area: Medicine
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DOI: 10.5272/jimab.2024301.5419
Published online: 12 March 2024

Original аrticle
J of IMAB. 2024 Jan-Mar;30(1):5419-5424
CLINICAL AND EPIDEMIOLOGICAL ANALYSIS ON SYPHILIS AMONG MEN WHO HAVE SEX WITH MEN
Hristina Haidudova1ORCID logo, Klimentina Gospodinova1ORCID logo, Milena Karcheva2ORCID logo, Dimitar Gospodinov1ORCID logoCorresponding Autoremail,
1) Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University, Pleven, Bulgaria.
2) Department of Infectious diseases, epidemiology, parasitology and tropical medicine, Faculty of Public Health, Medical University, Pleven, Bulgaria.

ABSTRACT:
Purpose of the study: To investigate demographics, prevalence, risk factors and the different clinical forms and symptoms of syphilis in men who have sex with men (MSM).
Material/Methods: 50 MSM with syphilis were registered at the Clinic of Dermatology and Venereology in the city of Pleven, Bulgaria, for the period 2008-2022. The diagnosis was confirmed by serological tests. Patients were distributed by their socio-demographic status. Risk factors and sexual behavior were studied, as well as clinical symptoms and co-morbidities of syphilis.
Results: Of 50 MSM patients the most affected is the age between 20-29 years (54%). 34% of them are university graduates, 88% abused alcohol, nicotine and drugs in combination, 70% had sexual contacts with a casual partner, 26% of them had HIV co-infection. Secondary and early latent syphilis are the most common clinical forms of the disease (34%). The typical symptoms of primary and secondary syphilis were clinically manifested, 34% of them are localized in the genital. There is a significant correlation of the clinical form with the localization of the skin-mucosal lesions (p < 0.001). Antibiotic therapy is effective and leads to negative serological test results by the end of the second year of treatment.
Conclusions: For 15 years (2008-2022), the number of registered MSM with syphilis in the Clinic of Dermatology and Venereology in Pleven increased after 2016 especialy in the time of the COVID-19 pandemic. Our results are close to the published data on the problem in the scientific literature for the last 10 years.

Keywords: sexually transmitted infections, risk factors, syphilides, MSM, HIV,

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Please cite this article as: Haidudova H, Gospodinova K, Karcheva M, Gospodinov D. Clinical and epidemiological analysis on syphilis among men who have sex with men. 2024 Jan-Mar;30(1):5419-5424. [Crossref - 10.5272/jimab.2024301.5419]

Corresponding AutorCorrespondence to: Dimitar Gospodinov, Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University, Pleven; 91, General Vladimir Vazov Str., Pleven-5800, Bulgaria; E-mail: dkg@abv.bg

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Received: 12 December 2023
Published online: 12 March 2024

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