head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2023, vol. 29, issue4
Subject Area: Dental Medicine
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DOI: 10.5272/jimab.2023294.5240
Published online: 30 November 2023

Review article
J of IMAB. 2023 Oct-Dec;29(4):5240-5244
AURICULOTEMPORAL NERVE AND FREY'S SYNDROME
Yanko Yankov1, 2ORCID logoCorresponding Autoremail,
1)Department of General and Operative Surgery, Faculty of Medicine, Medical University, Varna, Bulgaria.
2)Clinic of Maxillofacial Surgery, UMHAT "St. Marina", Varna, Bulgaria.

ABSTRACT:
Background: The auriculotemporal nerve is one of the main branches of the mandibular nerve. It provides sensory innervation to the auricle, the scalp in the temporal region, the temporomandibular joint and part of the dura mater, the parasympathetic innervation of the parotid salivary gland, as well as the external surface of the tympanic membrane, and the sympathetic innervation of the sweat glands and of the blood vessels passing through the parotid gland. Its interruption during surgical interventions or trauma can results in its most common disease - Frey's syndrome. This article is an overview and is based on 23 foreign scientific works - articles published in refereed and renowned scientific publications and anatomy atlases by world-renowned and proven specialists in their field.
Review Results: The auriculotemporal nerve is a sensory nerve which includes secretory parasympathetic vasomotor sympathetic fibers coming from the otic ganglion. It is a branch of the mandibular nerve (V3). Its five terminal nerve branches are front auricular branches, branches for the external auditory canal, branches for the temporomandibular joint, branches for the parotid gland and superficial temporal branches.
Frey's syndrome occurs when the auriculotemporal nerve is cut or injured proximal to the site of separation of the branches for the parotid gland or are severed themselves. The clinical picture characteristic of Frey's syndrome includes redness, sweating, warmth and itching in the area of innervation of the nerve and less often pain.
Conclusion: Knowledge of the anatomy of the auriculotemporal nerve and Frey's syndrome are essential for understanding its nature and stand on the basis of its prevention.

Keywords: auriculotemporal nerve, auriculotemporal syndrome, facial sweating, Frey's syndrome, mandibular nerve, parotidectomy,

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Please cite this article as: Yankov Y. Auriculotemporal Nerve and Frey’s Syndrome. J of IMAB. 2023 Oct-Dec;29(4):5240-5244. [Crossref - 10.5272/jimab.2023294.5240]

Corresponding AutorCorrespondence to: Yanko Yankov, MD, PhD, Clinic of Maxillofocial Surgery, UMHAT "Sveta Marina" - Varna; 1, floor 9, Hristo Smirnenski Blvd., Varna, Bulgaria; E-mail: yanko_1989@abv.bg

REFERENCES:
1.  Young A, Okuyemi OT. Frey Syndrome. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2023 Jan 12. [PubMed]
2. Greenberg JS, Breiner MJ. Anatomy, Head and Neck: Auriculotemporal Nerve. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing. 2023 Aug 8. [ PubMed ]
3. Fernandes PR, de Vasconsellos HA, Okeson JP, Bastos RL, Maia ML. The anatomical relationship between the position of the auriculotemporal nerve and mandibular condyle. Cranio. 2003 Jul;21(3):165-71. [PubMed]
4. Gray's Anatomy for Students, 2nd edition (2010), Drake Vogel and Mitchell, Elseview
5. Schmidt BL, Pogrel MA, Necoechea M, Kearns G. The distribution of the auriculotemporal nerve around the temporomandibular joint. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Aug;86(2):165-8. [PubMed]
6. Iwanaga J, Fisahn C, Watanabe K, Bobek SL, Ogata K, Tanoue R, et al. Parotid Branches of the Auriculotemporal Nerve: An Anatomical Study With Implications for Frey Syndrome. J Craniofac Surg. 2017 Jan;28(1):262-264. [PubMed]
7. Singh N, Kohli M, Kohli H. Innovative technique to reduce incidence of Frey's syndrome after parotid surgery. Am Surg. 2011 Mar;77(3):351-4.
8. Lee CC, Chan RC, Chan JY. Predictors for Frey Syndrome Development After Parotidectomy. Ann Plast Surg. 2017 Jul;79(1):39-41. [PubMed]
9. Kragstrup TW, Christensen J, Fejerskov K, Wenzel A. Frey syndrome-an underreported complication to closed treatment of mandibular condyle fracture? Case report and literature review. J Oral Maxillofac Surg. 2011 Aug;69(8):2211-6.
10. Blanc S, Bourrier T, Boralevi F, Sabouraud-Leclerc D, Pham-Thi N, Couderc L, et al. Frey Syndrome. J Pediatr. 2016 Jul;174:211-217.e2. [Crossref]
11. Linder TE, Huber A, Schmid S. Frey's syndrome after parotidectomy: a retrospective and prospective analysis. Laryngoscope. 1997 Nov;107(11 Pt 1):1496-501.
12. Motz KM, Kim YJ. Auriculotemporal Syndrome (Frey Syndrome). Otolaryngol Clin North Am. 2016 Apr;49(2):501-9. [PubMed]
13. Scully C, Langdon J, Evans J. Marathon of eponyms: 6 Frey syndrome (Gustatory sweating). Oral Dis. 2009 Nov;15(8):608-9. [PubMed]
14. Taylor SM, Yoo J, Matthews TW, Lampe HB, Trites JR. Frey's syndrome and parotidectomy flaps: A retrospective cohort study. Otolaryngol Head Neck Surg. 2000 Feb;122(2):201-3.
15. Fiacchini G, Cerchiai N, Tricò D, Sellari-Franceschini S, Casani AP, Dallan I, et al. Frey Syndrome, First Bite Syndrome, great auricular nerve morbidity, and quality of life following parotidectomy. Eur Arch Otorhinolaryngol. 2018 Jul;275(7):1893-1902. [PubMed]
16. Yu LT, Hamilton R. Frey's syndrome: prevention with conservative parotidectomy and superficial musculoaponeurotic system preservation. Ann Plast Surg. 1992 Sep;29(3):217-22.
17. Kornblut AD. Sternocleidomastoid muscle transfer in the prevention of Frey's syndrome. Laryngoscope. 1991 May;101(5):571-2.
18. Laage-Hellman JE. Treatment of gustatory sweating and flushing. Acta Otolaryngol. 1958 Mar-Apr;49(2):132-43. [PubMed]
19. Drobik C, Laskawi R. Frey's syndrome: treatment with botulinum toxin. Acta Otolaryngol. 1995 May;115(3):459-61.
20. Clayman MA, Clayman SM, Seagle MB. A review of the surgical and medical treatment of Frey syndrome. Ann Plast Surg. 2006 Nov;57(5):581-4.
21. Cassady CL. A new concept in the treatment of Frey's syndrome: the use of interpositional dermal grafts. An experimental study in the dog. Laryngoscope. 1977 Jun;87(6):962-74. [PubMed]
22. Smith RO, Hemenway WG, Stevens KM, Ratzer ER. Jacobson's neurectomy for Frey's syndrome. Am J Surg. 1970 Oct;120(4):478-81. 
23. Rubinstein RY, Rosen A, Leeman D. Frey syndrome: treatment with temporoparietal fascia flap interposition. Arch Otolaryngol Head Neck Surg. 1999 Jul;125(7):808-11.

Received: 19 May 2023
Published online: 30 November 2023

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