head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2023, vol. 29, issue4
Subject Area: Medicine
DOI: 10.5272/jimab.2023294.5201
Published online: 09 November 2023

Original article
J of IMAB. 2023 Oct-Dec;29(4):5201-5203
Mirena Valkova1ORCID logoCorresponding Autoremail, Ivanka Veleva2ORCID logo,
1) Neurology Clinic, University Hospital "Sofiamed", Sofia University "St. Kliment Ohridski", Bulgaria.
2) Department of psychiatry and medical psychology, Medical University Pleven, Bulgaria.

Introduction: Post-stroke depression (PSD) is one of the leading, although preventable complications, after ischemic stroke (IS). Our study aimed to examine PSD and the leading causes for its development
Contingent and methods: In this cross-sectional study, we examined 107 post-stroke survivors (66.67±9.03years old, 65 males and 42 females) for PSD in a two-step model (at the acute stage and at the 3rd month after stroke) with 21 Hamilton Depression Rating Scale (HDRS).
Results: 33% of examined patients showed depression at the acute and 30% at the chronicIS stage. 1/4 to 1/3 of the others had subclinical depression. The severity of depression in most of the cases was mild. Very few of our patients (2 at the acute tage and 1 at the chronic stroke stage) had severe depression. The main risk factors for PSD were stroke severity, subcortical localization of stroke, leukoaraiosis, ageing, loneliness and some comorbidities (that lead to systemic inflammation, changes in neurotransmission and impaired brain plasticity).
Conclusion:  PSD is one of the main complications of acute IS. It should be assessed, prevented and treated as soon as possible.

Keywords: post-stroke, depression, risk factors,

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Please cite this article as: Valkova M, Veleva I. Post-stroke depression and its risk factors – cross-sectional study. J of IMAB. 2023 Oct-Dec;29(4):5201-5203. [Crossref - 10.5272/jimab.2023294.5201]

Corresponding AutorCorrespondence to: Mirena Valkova, Neurology clinic, University Hospital "Sofiamed", Sofia University "St. Kliment Ohridski", Sofia, Bulgaria; E-mail: dr.plamenova@gmail.com

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Received: 24 April 2023
Published online: 09 November 2023

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