Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN:
1312-773X (Online)
Issue:
2023, vol. 29, issue3
Subject Area:
Medicine
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DOI:
10.5272/jimab.2023293.5125
Published online: 28 September 2023
Original article
J of IMAB. 2023 Jul-Sep;29(3):5125-5135
ANALYSIS OF MEDIUM-TERM RESULTS ACHIEVED AFTER MICROFRACTURES AND PERFORATIONS (DRILLING) IN LOCALIZED CHONDRAL LESIONS IN THE KNEE JOINT
Emil Simeonov


,
Department of Orthopedics and Traumatology, Faculty of Medicine, Medical University - Pleven, Bulgaria.
ABSTRACT:
Introduction: The main advantage of perforative techniques is their atraumatic, non-invasiveness and possibly being done under arthroscopic control.
Purpose: This study aims to compare two methods of operative techniques in the treatment of chondral lesions of the knee.
Materials and methods: The clinical study included 237 symptomatic patients with chondral defects from the period of 2010 – 2018. Patients were divided into 2 groups. The first group included 49 (32.11%) patients with arthroscopic micro-fractures. The second group included 54 (35.49%) patients with arthroscopic subchondral perforation (drilling). The term of follow-up was 36 months. Each patient had at least 4 documented follow-up visits.
Results: Results from grading scales – Lysholm, KOS, MRI – scales, as well as our own scale for evaluating knee function (PS) scale, were documented in each patient's separate file. The average pre-operative Lysholm score was 41.5 ± 6.6 in the microfracture group and 43.0 ± 5.6 in the perforation group. At the 36th-month average, Lysholm's score increased to 86.9 ± 7.3 in the microfracture group and to 86.1 ± 6.6 in the perforation group. During the study, it was also found that a correlation exists between the received results and the age of the patient, the size of the chondral defect, and the tracking period.
Conclusion: The effectiveness of osteoperforative techniques relies on many factors: the age of the patient, the size of the defect, and the tracking period. In the end, mesenchymal stimulation of chondrogenesis results in positive mid-term results in patients with small-sized chondral lesion.
Keywords: Arthroplasty, Subchondral, Knee Joint, Lysholm Knee Score,
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Please cite this article as: Simeonov E. Analysis of medium-term results achieved after microfractures and perforations (drilling) in localized chondral lesions in the knee joint. J of IMAB. 2023 Jul-Sep;29(3):5125-5135. [Crossref - 10.5272/jimab.2023293.5125]
Correspondence to: Dr. Emil Simeonov, MD, PhD, Clinic of Orthopedics & Traumatology, UMBAL “Dr. Georgi Stranski“ – Pleven; 89, Ruse Str., Pleven 5803, Bulgaria; E-mail: emil.simeonov.pl@gmail.com
REFERENCES:
1. Mano JF, Reis RL. Osteochondral defects: present situation and tissue engineering approaches. J Tissue Eng Regen Med. 2007 Jul-Aug;1(4):261-73. [PubMed]
2. Litwic A, Edwards MH, Dennison EM, Cooper C. Epidemiology and burden of osteoarthritis. Br Med Bull. 2013;105:185-99. [PubMed]
3. Willers C, Wood DJ, Zheng MH. A current review on the biology and treatment of articular cartilage defects (part I&part II). J Musculoskelet Res. 2003 Sep-Dec;7(3-4):157-81. [Crossref]
4. Gracitelli GC, Moraes VY, Franciozi CE, Luzo MV, Belloti JC. Surgical interventions (microfracture, drilling, mosaicplasty, and allograft transplantation) for treating isolated cartilage defects of the knee in adults. Cochrane Database Syst Rev. 2016 Sep 3;9(9):CD010675. [PubMed]
5. Sophia Fox AJ, Bedi A, Rodeo SA. The basic science of articular cartilage: structure, composition, and function. Sports Health. 2009 Nov;1(6):461-8. [PubMed]
6. E Albuquerque RP, Giordano V, Calixto A, Malzac F, Aguiar C, do Amaral NP, et al. Analysis on the modified Lysholm functional protocol among patients with normal knees. Rev Bras Ortop. 2015 Nov 16;46(6):668-74. [PubMed]
7. Howell M, Liao Q, Gee CW. Surgical Management of Osteochondral Defects of the Knee: An Educational Review. Curr Rev Musculoskelet Med. 2021 Feb;14(1):60-66. [PubMed]
8. Steadman JR, Rodkey WG, Briggs KK. Microfracture: Its History and Experience of the Developing Surgeon. Cartilage. 2010;1(2):78-86. [PubMed]
9. Mithoefer K, Williams RJ 3rd, Warren RF, Potter HG, Spock CR, Jones EC, et al. Chondral resurfacing of articular cartilage defects in the knee with the microfracture technique. Surgical technique. J Bone Joint Surg Am. 2006 Sep;88 Suppl 1 Pt 2:294-304 [PubMed]
10. Erggelet C, Vavken P. Microfracture for the treatment of cartilage defects in the knee joint - A golden standard? J Clin Orthop Trauma. 2016 Jul-Sep;7(3):145-52. [PubMed]
11. Bae DK, Yoon KH, Song SJ. Cartilage healing after microfracture in osteoarthritic knees. Arthroscopy. 2006 Apr;22(4):367-74. [PubMed]
12. Gobbi A, Nunag P, Malinowski K. Treatment of full thickness chondral lesions of the knee with microfracture in a group of athletes. Knee Surg Sports Traumatol Arthrosc. 2005 Apr;13(3):213-21. [PubMed]
13. Knutsen G, Drogset JO, Engebretsen L, Grшntvedt T, Isaksen V, Ludvigsen TC, et al. A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years. J Bone Joint Surg Am. 2007 Oct;89(10):2105-12. [PubMed]
14. Miller BS, Steadman JR, Briggs KK, Rodrigo JJ, Rodkey WG. Patient satisfaction and outcome after microfracture of the degenerative knee. J Knee Surg. 2004 Jan;17(1):13-7. [PubMed]
15. Mithoefer K, Williams RJ 3rd, Warren RF, Potter HG, Spock CR, Jones EC, et al. The microfracture technique for the treatment of articular cartilage lesions in the knee. A prospective cohort study. J Bone Joint Surg Am. 2005 Sep;87(9):1911-20. [PubMed]
16. Steadman JR, Briggs KK, Rodrigo JJ, Kocher MS, Gill TJ, Rodkey WG. Outcomes of microfracture for traumatic chondral defects of the knee: average 11-year follow-up. Arthroscopy. 2003 May-Jun;19(5):477-84. [PubMed]
17. Kreuz PC, Steinwachs MR, Erggelet C, Krause SJ, Konrad G, Uhl M, et al. Results after microfracture of full-thickness chondral defects in different compartments in the knee. Osteoarthritis Cartilage. 2006 Nov;14(11):1119-25. [PubMed]
18. Mithoefer K, McAdams T, Williams RJ, Kreuz PC, Mandelbaum BR. Clinical efficacy of the microfracture technique for articular cartilage repair in the knee: an evidence-based systematic analysis. Am J Sports Med. 2009 Oct;37(10):2053-63. [PubMed]
19. Steadman JR, Rodkey WG, Briggs KK. Microfracture to treat full-thickness chondral defects: surgical technique, rehabilitation, and outcomes. J Knee Surg. 2002 Summer;15(3):170-6. [PubMed]
20. Bobic V, Morgan CD, Carter T. Osteochondral autologous graft transfer. Oper Tech Sports Med. 2000 Apr;8(2):168-178. [Crossref]
21. Mithöfer K, Peterson L, Mandelbaum BR, Minas T. Articular cartilage repair in soccer players with autologous chondrocyte transplantation: functional outcome and return to competition. Am J Sports Med. 2005 Nov;33(11):1639-46. [PubMed]
22. Gudas R, Kalesinskas RJ, Kimtys V, Stankevicius E, Toliusis V, Bernotavicius G, et al. A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes. Arthroscopy. 2005 Sep;21(9):1066-75. [PubMed]
23. Gobbi A, Francisco RA, Lubowitz JH, Allegra F, Canata G. Osteochondral lesions of the talus: randomized controlled trial comparing chondroplasty, microfracture, and osteochondral autograft transplantation. Arthroscopy. 2006 Oct;22(10):1085-92. [PubMed]
Received: 18 May 2023
Published online: 28 September 2023
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