head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2023, vol. 29, issue3
Subject Area: Medicine
-
DOI: 10.5272/jimab.2023293.5094
Published online: 12 September 2023

Review article
J of IMAB. 2023 Jul-Sep;29(3):5094-5098
COMPARATIVE ANALYSIS OF PANDEMICS HIV/AIDS AND COVID-19
Mariyana Stoycheva1ORCID logo, Nikolay Vatev2ORCID logo, Milena Karcheva3ORCID logoCorresponding Autoremail,
1) Department of Infectious Diseases, Parasitology and Tropical Medicine, Faculty of Medicine, Medical University - Plovdiv, Bulgaria.
2) Department of Epidemiology and Disaster Medicine, Faculty of Public Health, Medical University - Plovdiv, Bulgaria.
3) Department of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine, Faculty of Public Health, Medical University - Pleven, Bulgaria.

ABSTRACT:
During recent four decades, the world has faced two horrific, deadly pandemics. In the background of the ongoing pandemic HIV/AIDS, the people were affected with the newly emerging Corona virus SARS-CoV-2, that rapidly turned into pandemic dimensions. There are data that, in various aspects, HIV infection was similar to SARS-CoV-2. The purpose of this review was to search for similarities and differences between both pandemics in view to use the experience of the past and knowledge we have acquired in order to better overcome current and future pandemics.  
Material/Methods: The iterature used is based on databases PubMed, Embase and random search on the Internet with the keywords COVID-19 and HIV, as well the Boolean operator  "AND" to achieve a search of "COVID-19 and HIV".
Review Results: In the present review summary, we provide data for similarities and differences regarding virological, immunologic, clinical and pharmacological aspects of HIV and SARS-CoV-2 infections and associated with them pandemics.
Conclusion:  SARS-CoV-2 was here and will remain here. COVID-19 is not the last pandemic, and people should be prepared for new encounters with agents of high virulence and pandemic potential.

Keywords: pandemics, COVID-19, HIV/AIDS, similarities, differences,

pdf - Download FULL TEXT /PDF 502 KB/
Please cite this article as: Stoycheva M, Vatev N, Karcheva M. Comparative analysis of pandemics HIV/AIDS and COVID-19. J of IMAB. 2023 Jul-Sep;29(3):5094-5098.
[Crossref - 10.5272/jimab.2023293.5094]

Corresponding AutorCorrespondence to: Prof. Milena Karcheva, MD, PhD, Department of Infectious Diseases, Epidemiology, Parasitology and Tropical medicine, Faculty of Public Health, Medical University-Pleven; 1, “Sv. Kl. Ohridski" Str. Pleven, Bulgaria; E-mail: milena_karcheva@abv.bg

REFERENCES:
1. Cooper B, Toskin I, Kulier R, Allen T, Hawkes S. Brief sexuality communication - A behavioural intervention to advance sexually transmitted infection/HIV prevention: A systematic review. BJOG. 2014 Oct;121 Suppl 5:92-103. [PubMed]
2. Global HIV & AIDS statistics - Fact sheet. UNAIDS. 2022. [Internet]
3. May RM, Anderson RM. The transmission dynamics of human immunodeficiency virus (HIV). Philos Trans R Soc Lond B Biol Sci. 1988 Oct 31;321(1207):565-607. [PubMed]  
4. Andersen KG, Rambaut A, Lipkin WI, Holmes EC, Garry  RF. The proximal origin of SARS-CoV-2. Nat Med. 2020 Apr;26(4):450-452. [PubMed]
5. Makoti P, Fielding BC. HIV and Human Coronavirus Co-infections: A Historical Perspective. Viruses. 2020 Aug 26;12(9):937. [PubMed]
6. Lorenzo-Redondo R, Ozer EA, Achenbach CJ, D'Aquila RT, Hultquist JF.Molecular epidemiology in the HIV and SARS-CoV-2 pandemics. Curr Opin HIV AIDS. 2021 Jan;16(1):11-24. [ PubMed ]
7. Dawa N, Narain JP. COVID-19 & HIV/AIDS pandemics: Parallels & lessons. Indian J Med Res. 2021 Jan-Feb;153(1-2):214-218. [PubMed]
8. Hargreaves J, Davey C and the Group for lessons from pandemic HIV prevention for the COVID-19 response. Three lessons for the COVID-19 response from pandemic HIV. Lancet HIV. 2020 May;7(5):e309-e311. [PubMed]
9. Tang X, Wu C, Li X, Song Y, Yao X, Wu X, et al. On the origin and continuing evolution of SARS-CoV-2. NatlSci Rev. 2020 Jun;7(6):1012-1023. [Crossref]
10. UNAIDS data 2020. Documents. 06 July 2020. [Internet]
11. Fintelman-Rodrigues N, Sacramento CQ, Ribeiro Lima C, Souza da Silva F, Ferreira AC, Mattos M, et al. Atazanavir, Alone or in Combination with Ritonavir, Inhibits SARS-CoV-2 Replication and Proinflammatory Cytokine Production. Antimicrob Agents Chemother. 2020 Sep 21;64(10):e00825-20. [PubMed]
12. Zhang Y, Geng X, Tan Y, Li Q, Xu C, Xu J, et al. New understanding of the damage of SARS-CoV-2 infection outside the respiratory system. Biomed Pharmacother. 2020 Jul;127:110195. [PubMed]
13. Wu C, Chen X, Cai Y, Xia J, Zhou X, Xu S, et al. Risk Factors Associated With Acute Respiratory Distress Syndrome and Death in Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. JAMA Intern Med. 2020 Jul 1;180(7):934-943. [PubMed]
14. Blanco JL, Ambrosioni J, Garcia F, Martínez E, Soriano A, Mallolas J, et al. COVID-19 in patients with HIV: clinical case series. Lancet HIV. 2020 May;7(5):e314-e316. [PubMed]
15. RECOVERY Collaborative Group. Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet. 2020 Oct 24;396(10259):1345-1352. [PubMed]
16.  Cao  B, Wang  Y, Wen  D, Liu  W , Wang  J , Fan  G, et al. A Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19. N Engl J Med. 2020 May 7;382(19):1787-1799. [PubMed]
17. Chan JF, Yao Y, Yeung ML, Deng W, Bao L, Jia L, et al. Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common Marmoset. J Infect Dis. 2015 Dec 15;212(12):1904-13. [PubMed]
18. Phan T. Genetic diversity and evolution of SARS-CoV-2. Infect Genet Evol. 2020 Jun;81:104260. [PubMed]
19. Brown LB, Spinelli MA, Gandhi M. The Interplay between HIV and COVID-19: summary of the data and responses to date. Curr Opin HIV AIDS. 2021 Jan;16(1):63–73. [PubMed]
20. Lu S. Timely development of vaccines against SARS-CoV-2. Emerg Microbes Infec.2020 Mar 8;9(1):542-544. [PubMed]
21. Zhu F, Cao Y, Xu S, Zhou M. Co-infection of SARS-CoV-2 and HIV in a patient in Wuhan city, China. J Med Virol. 2020 Jun;92(6):529-530. [PubMed]

Received: 22 February 2023
Published online: 12 September 2023

back to Online Journal