head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2023, vol. 29, issue1
Subject Area: Medicine
DOI: 10.5272/jimab.2023291.4814
Published online: 14 February 2023

Original article
J of IMAB. 2023 Jan-Mar;29(1):4814-4819
Georgi Lazarov1ORCID logo Corresponding Autoremail, Philip Kumanov2ORCID logo, Vladislav Mladenov3ORCID logo,
1) Аndrological office, Hospital in obstetrics and gynecology "St. Sofia", Sofia, Bulgaria.
2) Medical Center „Аcademician Ivan Penchev“, Sofia Bulgaria.
3) Department of Urology, UMBAL Alexandrovska, Sofia, Bulgaria.

In our outpatient practice, we are increasingly seeing men aged 35 to 45 years who have permanent low normal testosterone levels.
Aim We set out to investigate whether there is an association between permanent low normal testosterone levels and lower urinary tract symptoms in young men.
Patients and Methods For the period from January 2013 to December 2015 at the Andrology office at Hospital "St. Sofia", we examined 73 men aged 35 to 45 years with normal or elevated body mass index, permanent low normal testosterone level and micturition disorders. In order to compare the results we obtained, at the very beginning of the study, we selected a control group of 20 healthy men of the same age.
Results We obtained, although within reference ranges, significantly lower values for total testosterone in the 73 men with micturition disorders we studied, compared with those in the control group without micturition disorders.
1. Our study shows that in some men at a young age, some deviation in normal testosteronе secretion occurs, with a concomitant decrease in maximum urine flow, which is remarkably different from the same indicator in their peers with a high normal testosterone level.
2. We identify permanent low normal testosterone, overweight, and obesity as predictors of initial lower urinary tract symptoms in young men.
3. According to our study, the altered E2/T ratio is also relevant to the initial onset of lower urinary tract symptoms in young men.

Keywords: testosterone, estradiol, BMI, LUTS,

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Please cite this article as: Lazarov G, Kumanov P, Mladenov V. Permanent low normal testosterone and lower urinary tract symptoms in men 35 - 45 years of age. J of IMAB. 2023 Jan-Mar;29(1):4814-4819. DOI: 10.5272/jimab.2022281.4814

Corresponding AutorCorrespondence to: Georgi Lazarov, MD, Hospital in obstetrics and gynecology "St. Sofia"; 11, W. Gladston Str., 1000 Sofia, Bulgaria; E-mail: doctorlazarov@abv.bg

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Received: 14 November 2022
Published online: 14 February 2023

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