head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2022, vol. 28, issue4
Subject Area: Medicine
DOI: 10.5272/jimab.2022284.4735
Published online: 14 December 2022

Original article
J of IMAB. 2022 Oct-Dec;28(4):4735-4737
Biser Borisov1ORCID logo Corresponding Autoremail, Elena Borisova2ORCID logo, Desislava Lubomirova3ORCID logo, Pavlina Glogovska2ORCID logo,
1) Department of Nephrology and Dialysis, Faculty of Medicine, Medical University, Pleven, Bulgaria.
2) Department of Pulmonology and Phtisiology, Faculty of Medicine, Medical University, Pleven, Bulgaria.
3) Department of Gastroenterology, Faculty of Pharmacy, Medical University, Pleven, Bulgaria.

Purpose: Since its inception in early 2020, COVID-19 has quickly become a pandemic, killing more than six million people worldwide. The aim of this study is to investigate the morbidity and mortality of COVID-19 in one Bulgarian hemodialysis center.
Materials and methods: The study is retrospective, conducted for the period of 25th Apr 2020 – 31st Dec 2021. The mean annual number of hemodialysis patients was 184, including patients with end-stage renal disease and acute renal failure. The total number of patients with COVID-19 was 78 (42%), 49of which (63%) were males, the average age was 60 years (+/-12.1 years).
Results: There was no significant difference between the mean age of patients divided by sex (p=0.069). A total of 33 people died (42%), 17 of whom (51%) were males. The average age of the deceased patients (64.24 +/- 10.846) was higher than that of the survivors (58.44 +/-12.286), and the difference was significant (p=0.034). There was no significant difference in the mean age of survived and deceased males (p=0.74) but for females, the difference was statistically significant – the mean age of survivorswas 55.00 (+/-12.03)and of the deceased patients was 67.6 (+/- 8.79) years.
Conclusion: Our results confirm data from similar studies aboutthe high incidence and mortality of COVID-19 in hemodialysis patients. We confirma statistically significant increase in mortality of these patients with increasing age. Probably the mass vaccination of patients and staff; the use of antiviral drugs and biological therapy is the way to reduce morbidity and mortality among them.

Keywords: end-stage renal disease, hemodialysis, COVID-19 - morbidity and mortality,

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Please cite this article as: Borisov B, Borisova E, Lubomirova D, Glogovska P. Morbidity and Mortality from COVID-19 in a Dialysis Center in Northern Bulgaria. J of IMAB. 2022 Oct-Dec;28(4):4735-4737. DOI: 10.5272/jimab.2022284.4735

Corresponding AutorCorrespondence to: Biser Borisov, MD. PhD., Department of Nephrology and Dialysis, Faculty of Medicine, Medical University, Pleven; 8A, George Kochev Str., Pleven 5800, Bulgaria; E-mail: biserugo@abv.bg

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Received: 04 July 2022
Published online: 14 December 2022

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