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Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2021, vol. 27, issue2
Subject Area: Dental Medicine
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DOI: 10.5272/jimab.2021272.3817
Published online: 28 June 2021
Original article
J of IMAB. 2021 Apr-Jun;27(2):3817-3822
CORRELATION BETWEEN SLEEP APNEA AND METHADONE THERAPY
Christiana Madjova1
, Simeon Chokanov1, Mario Milkov2,
1) Department of Conservative Dentistry and Oral Pathology, Faculty of Dental Medicine, Medical University – Varna
2) Department of Dental Materials Science, and Propaedeutics of Prosthetic Dental Medicine, Faculty of Dental Medicine, Medical University – Varna, Bulgaria.
ABSTRACT:
Introduction: Methadone therapy is the mainstay of treatment of addict patients. The most common side effects are: dizziness, drowsiness, vomiting, sweating, dry mouth and constipation. The more serious complications that can be observed are: sleep apnea, аbnormal heart rhythms, respiratory problems, euphoria, disorientation, anxiety, seizures and more.
Purpose: The purpose of this study is to determine the correlation between methadone maintenance treatment and sleep apnea in addict patients.
Materials and methods: The subject of the study are 81 methadone-treated drug-dependent patients, mean age 39 ± 9,07 years.
Results: The answers we received: 79% (64) of drug addicts have problems with sleep; 30.9% of them (25) reported having insomnia; 44.4% (36) experience morning fatigue; 56.8% (46) of the respondents said they were drowsy during the day and 63% of the respondents reported a change in mood; 21% (17) had a short sleep, and 26% (21)reported snoring and 18 of them have loud bothering snoring; 68% answered that they don't have problems with falling asleep and only 21% don’t wake up frequently in the evening. In 83.9% nobody noticed cessation of breathing during sleep. 73.8% never nodded off or fallen asleep while driving a vehicle. 16.1% have been treated for high blood preasure, and only 2.5% have obesity.
Conclusions: Our survey found that there is a correlation between methadone therapy and sleep of patients. The key to improving the condition and reducing the risk of central sleep apnea is the monitoring of patients, as well as a combination of different types of treatment.
Keywords: Methadone, Opiate dependence, Drug addicts, Sleep apnea, Central sleep apnea, Sleep disorders,
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Please cite this article as: Madjova C, Chokanov S, Milkov M. Correlation between sleep apnea and methadone therapy. J of IMAB. 2021 Apr-Jun;27(2):3817-3822. DOI: 10.5272/jimab.2021272.3817
Correspondence to: Christiana Madjova, Department of Conservative Dentistry and oral pathology, Faculty of Dental Medicine, Medical University – Varna; 84, TzarOsvoboditel Blvd., 9000 Varna, Bulgaria; E-mail: christiana.madjova@gmail.com
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Received: 24 June 2020
Published online: 28 June 2021