head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2021, vol. 27, issue2
Subject Area: Medicine
DOI: 10.5272/jimab.2021272.3793
Published online: 08 June 2021

Review article

J of IMAB. 2021 Apr-Jun;27(2):3793-3798
Yordanka Doneva1,2ORCID logo Corresponding Autoremail, Veselin Valkov1,4ORCID logo, Yavor Kashlov1,2ORCID logo, Galya Mihaylova3ORCID logo, Atanas Angelov2,4ORCID logo, Maria Radanova3ORCID logo,
1) Department of Propedeutics of Internal Medicine, Medical University of Varna, Bulgaria.
2) Department of Internal Medicine, UMHAT “St. Marina”, Varna, Bulgaria.
3) Department of Biochemistry, Molecular Medicine and Nutrigenomics, Medical University of Varna, Bulgaria.
4) First Clinic of Cardiology, UMHAT St. Marina, Varna, Bulgaria.

Circular RNA (circRNAs) belong to the long non-coding RNA family, but unlike the linear RNA in circular RNA, the 3’ and 5’ end in the RNA molecule are joined together, forming their circular structure. Until recently, circRNAs have been believed to be a side product of splicing, but now it is known that they have a wide range of biological functions, from regulators of gene expression to regulators of other non-coding RNAs - microRNAs (miRNAs). CircRNAs have the potential  of being therapeutic targets and biomarkers for diseases. There are little data and only several investigations about this type of RNAs in myocardial infarction in humans.
This review summarizes the role of some new circRNA – miRNA interactions in the development of Myocardial Infarction.

Keywords: CircRNAs, miRNAs, myocardial infarction,

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Please cite this article as: Doneva Y, Valkov V, Kashlov Y, Mihaylova G, Angelov A, Radanova M. Circular RNA – miRNA mediated interaction in Myocardial Infarction. J of IMAB. 2021 Apr-Jun;27(1):3793-3798. DOI: 10.5272/jimab.2021272.3793

Corresponding AutorCorrespondence to: Yordanka Doneva, UMBAL ”St. Marina”-Varna; 1, Hristo Smirnenski Blvd., Varna, Bulgaria; E-mail: d12_doneva@abv.bg

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Received: 16 December 2020
Published online: 08 June 2021

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