head JofIMAB
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing Ltd.
ISSN: 1312-773X (Online)
Issue: 2020, vol. 26, issue2
Subject Area: Dental Medicine
DOI: 10.5272/jimab.2020262.3187
Published online: 11 June 2020

Case report

J of IMAB. 2020 Apr-Jun;26(2):3187-3193
Elitsa Deliverska1ORCID logo Corresponding Autoremail, Evgenii Hadjiev2, Lutchezar Stefanov1, Gergana Tsvetkova2, Emel Bekirova2, Sadeta Parusheva1ORCID logo,
1) Department of Dental, Oral and Maxillofacial surgery, Faculty of Dental Medicine, Medical University - Sofia.
2) Clinic of Clinical Hematology, UMHAT “Alexandrovska” - Sofia, Bulgaria.

Background: Lymphoma in a single bone without any nodal or visceral involvement is known as primary intra-osseous lymphoma, which is a very uncommon malignancy. It constitutes 3.1% of malignant bone tumours and 5% of extranodal lymphomas, and the incidence is only 0.6% in the jaws. These tumours can be primary or secondary (in the disseminated forms).  The primary intra-osseous lymphoma of the jaws is a challenge to diagnose, because of their various clinical presentation, which can mimic an odontogenic tumour, cyst or a fibro-osseous lesion.
Purpose: This case report discusses a rare malignancy of jaw bones, including clinical presentation, histopathologic features, immunologic profile, PET scan, management and prognosis.
Material and methods: We present a case of a primary intraosseous lymphoma in a 45-year-old female who presented with a swelling in the right maxilla. It highlights the importance of recognizing rare entities that may present in the jaws, the impact of the disease and its management.
Results: Jaw localization of Non-Hodgkin’s lymphoma is rare. Clinical symptomatology and radiological signs are poorly contributive. The diagnosis relies on the histopathological analysis.
Conclusion: One of the diagnostic problems with regard to NHL is the variable nature of clinical symptoms. A biopsy allowed diagnosing an intra-oral bone lymphoma, and the patient was referred to the hematooncology unit for treatment.

Keywords: non Hodgkin’s lymphoma, extranodal, jaws,

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Please cite this article as: Deliverska E, Hadjiev E, Stefanov L, Tsvetkova G, Bekirova E, Parusheva S. Primary Extranodal Non-Hodgkin’s Lymphoma Involving Right Maxilla. J of IMAB. 2020 Apr-Jun;26(2):3187-3193. DOI: 10.5272/jimab.2020262.3187

Corresponding AutorCorrespondence to: Elitsa Georgieva Deliverska, Department of Dental, Oral and Maxillofacial surgery, Faculty of Dental Medicine, Medical University- Sofia; 1, Georgi Sofiiski Blvd., Sofia 1431, Bulgaria; E-mail: elitsadeliverska@yahoo.com

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Received: 01 July 2019
Published online: 11 June 2020

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