Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski Publishing
ISSN:
1312-773X (Online)
Issue:
2018, vol. 24, issue2
Subject Area:
Medicine
-
DOI:
10.5272/jimab.2018242.2030
Published online: 14 June 2018
Case report
J of IMAB. 2018 Apr-Jun;24(2):2030-2033
PERIOCULAR METASTASIS ASSOCIATED WITH COLORECTAL CARCINOMA
Zornitsa I. Zlatarova1, 2 , Anna N. Ilieva1, 2, Ivan Y. Krasnaliev3
1) Department of Ophthalmology and Visual Science, Medical University - Varna, Bulgaria.
2) Specialized Eye Hospital - Varna, Bulgaria.
3) Department of General and Clinical Pathology, Forensic Medicine and Deontology, Medical University - Varna, Bulgaria.
ABSTRACT:
Purpose: To present a case of a 69-year old woman with periocular metastatic disease.
Methods: Standard ophthalmic examination combined with CT and PET/CT imaging, surgical excision of the tumour and histopathological and immunohistochemical examination.
Results: Patient presents with large solid lesion in left lateral eyelid angle. After surgical excision histopathological examination shows metastatic moderately to poorly differentiated rectal adenocarcinoma. PET/CT shows whole body subcutaneous metastases. Patient receives chemotherapy and eighteen months after eyelid surgery is without local recurrence.
Conclusions: Periocular metastasis can present with nonspecific features and should be considered in patients with known systemic malignancy. Treatment and follow up of these patients is multidisciplinary team work.
Keywords: periocular metastasis, eyelid metastasis, metastatic colorectal carcinoma, spontaneous healing,
- Download FULL TEXT /PDF 1498 KB/
Please cite this article as: Zlatarova ZI, Ilieva AN, Krasnaliev IY. Periocular metastasis associated with colorectal carcinoma. J of IMAB. 2018 Apr-Jun;24(2):2030-2033. DOI: 10.5272/jimab.2018242.2030
Correspondence to: Assoc. Prof. Zornitsa I. Zlatarova MD, PhD, DSc, Department of Ophthalmology and Visual Science, Medical University - Varna; Specialized Eye Hospital – Varna; 15, Doyran str., Varna 9002, Bulgaria; E-mail: zzlatarova@abv.bg,
REFERENCES:
1. Bianciotto C, Demirci H, Shields CL, Eagle RC Jr, Shields JA. Metastatic Tumors to the Eyelid: Report of 20 Cases and Review of the Literature. Arch Ophthalmol. 2009; 127(8):999-1005. [PubMed] [CrossRef]
2. Wang JK, Liao SL, Jou JR, Lai PC, Kao SC, Hou PK, et al. Malignant eyelid tumours in Taiwan. Eye (Lond) 2003 Mar;17(2):216-20. [PubMed] [CrossRef]
3. Jakobiec FA, Stagner AM, Homer N, Yoon MK. Periocular Breast Carcinoma Metastases: Predominant Origin From the Lobular Variant. Ophthal Plast Reconstr Surg. 2017 Sep/Oct;33(5):361-6. [PubMed] [CrossRef]
4. Mudhar HS, Nuruddin M, Roy SR. Eyelid Metastatic Thyroid Papillary Carcinoma. Ocul Oncol Pathol. 2016 Apr;2(3):156-9. [PubMed] [CrossRef]
5. Joseph SS, Yentz SE, Mikkilineni S, Nelson C, Kalemkerian GP. Eyelid Metastasis in Non-Small Cell Lung Cancer: Diagnosis and Management. Am J Med 2016 Sep; 129(9):e169-172. [PubMed] [CrossRef]
6. Fonseca NL Jr, Lucci LM, Cha SB, Rossetti C, Rehder JR. Metastatic eyelid disease associated with primary breast carcinoma: case report. Arq Bras Oftalmol 2009 May-Jun;72(3):390-3. [PubMed] [CrossRef]
7. Arnold AC, Bullock JD, Foos RY. Metastatic eyelid carcinoma. Ophthalmology. 1985 Jan;92(1):114-9. [PubMed] [CrossRef]
8. Riley FC. Metastatic tumors of the eyelids. Am J Ophthalmol. 1970 Feb;69(2):259-64. [PubMed] [CrossRef]
9. Goel S, Mittal DK, Sharma P, Rover RK. An unusual case of eyelid metastasis from a rectal primary. J Cancer Res Ther. 2015 Oct-Dec; 11(4):1032. [PubMed] [CrossRef]. .
Received: 16 April 2018
Published online: 14 June 2018
back to Online Journal