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Publisher: Peytchinski Publishing
ISSN: 1312-773X (Online)
Issue: 2018, vol. 24, issue2
Subject Area: Dental Medicine
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DOI: 10.5272/jimab.2018242.1995
Published online: 17 May 2018
Case report
J of IMAB. 2018 Apr-Jun;24(2):1995-1997
MIKULICZ’S SYNDROME ASSOCIATED WITH LEUKEMIA: A CASE REPORT
Elitsa Deliverska1
, Lutchezar Stefanov1, Evgueniy Hadjiev2, Zornitsa Mihaylova1 
, Dobrina Karayasheva3,
1) Department of Oral and maxillofacial surgery, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria
2) Department of Haematology, Medical Faculty, Medical University - Sofia, Bulgaria
3) Department of Conservative dentistry, Faculty of Dental Medicine, Medical University - Sofia, Bulgaria.
ABSTRACT:
Mikulicz’s syndrome is a chronic swelling of the lacrimal and major salivary glands usually associated with significantly decreased or lack of lacrimation and xerostomia, accompanied by lymphocytic infiltration. It is associated with other entities like tuberculosis, lupus erythematosus, lymphoma, leukemia, etc.
A case of 70 years old man with painless, dense swelling of the left parotid gland and medical history of leukemia is presented. The decreased secretory activity of the parotid gland is observed. The patient is referred for laboratory blood test and ultrasound examination of the parotid glands. Mikulicz’s syndrome associated with acute myelogenous leukemia was identified. Laboratory blood test reveals leukocytosis (118 g/L). The progress of the glands pathology seems to be associated with the severity of the main disease and appears to be a poor prognostic sign. Based on the findings the definitive diagnosis in the reported case is Mikulicz’s syndrome associated with leukemia. The swelling is expected to disappear spontaneously or after treatment with corticosteroids. However, paliative treatment was conducted due to the severity of the systemic disease.
Keywords: Mikulicz’s syndrome, salivary gland swelling, Extranodal lymphoid infiltrates,
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Please cite this article as: Deliverska E, Stefanov L, Hadjiev E, Mihaylova Z, Karayasheva D. Mikulicz’s syndrome associated with leukemia: a case report. J of IMAB. 2018 Apr-Jun;24(2):1995-1997. DOI: 10.5272/jimab.2018242.1995
Correspondence to: Dr Zornitsa Mihaylova, Department of Oral and maxillofacial surgery, Faculty of Dental medicine, Medical University – Sofia; 1, St. George Sofiyski str., 1431 Sofia, Bulgaria; E-mail: zorrymihaylova@gmail.com,
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Received: 22 January 2018
Published online: 17 May 2018