Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev ET
ISSN: 1312-773X (Online)
Issue: 2017, vol. 23, issue 1
Subject Area: Medicine
Pages: 1444-1446
DOI: 10.5272/jimab.2017231.1444
Published online: 25 January 2017

J of IMAB 2017 Jan-Mar;23(1):1444-1446
Petko Marinov1, 4 Snezha Zlateva1, 4, Georgi Bonchev1ORCID logoCorresponding Autor, Dobri Ivanov2, Kaloyan Georgiev3, Yulichka Sabeva4, Marieta Yovcheva1.
1) Clinic for Intensive Treatment of Acute Intoxications and Toxicoallergies, Naval Hospital – Varna, Military Medical Academy, Bulgaria
2) Department of Biology, Faculty of Pharmacy, Medical University – Varna, Bulgaria
3) Department of Pharmaceutical Technologies, Faculty of Pharmacy, Medical University – Varna, Bulgaria
4) Department of Pharmacology, Toxicology and Pharmacotherapy, Faculty of Pharmacy, Medical University – Varna, Bulgaria.

Purpose: Poisoning with drugs is a serious medical and social problem worldwide. Retrospective analysis of acute poisoning with narcotic drugs had been performed in Varna region for 25 years (1991-2015).
Material and Methods: The number of patients received hospital treatment after poisonings with narcotic substances was 677, which represented 3.9% of all acute exogenous intoxications.
Results: Narcotic poisonings were more common in men – 546 (80.6%), than in women – 131 (19.4 %). The ratio male/ female was 4.17:1. The largest number of intoxications were in the age group up to 24 years – 1123 (66%), and only 2.65% of patients were over 45 years. Death was registered in 6 (0.9%) patients.

Key words: narcotics, drug poisoning, drug lethality, heroin, amphetamines, opiates, cocaine, ecstasy,

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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Marinov P, Zlateva S, Bonchev G, Ivanov D, Georgiev K, Sabeva Y, Yovcheva M. ACUTE NARCOTIC DRUG INTOXICATIONS: ETIOLOGY, SEX/AGE DISTRIBUTION AND CLINICAL OUTCOME. J of IMAB. 2017 Jan-Mar;23(1):1444-1446. DOI: 10.5272/jimab.2017231.1444.

Correspondence to: Georgi Bonchev, PhD; Head, Laboratory of Analytical Toxicology, Military Medical Academy, Naval Hospital – Varna; 3, Hristo Smirnenski Blvd., 9010 Varna, Bulgaria; E-mail:

1. Marijuana. National Institute on Drug Abuse. updated 2016 February. [Internet]
2. World Drug Report 2014. Cannabis. Vienna: United Nations Office on Drugs and Crime; 2014 June 26. [Internet]
3. Wollner K, Stockhausen S, Musshoff F, Madea B. [Death after the intake of amphetamine/ecstasy: two case reports.] [in German] Arch Kriminol. 2015 Jan-Feb;235(1-2):53-61. [PubMed]
4. Westover AN, Nakonezny PA, Haley RW. Acute myocardial infarction in young adults who abuse amphetamines. Drug Alcohol Depend. 2008 Jul;96(1-2):49-56. [PubMed]
5. World Drug Report 2014. Amphetamine-type stimulants. United Nations Office on Drugs and Crime; 2014 June 26. [Internet]
6. Data and Statistics. National Institute on Drug Abuse; 2013 October 7. [Internet]
7. Huang B, Dawson DA, Stinson FS, Hasin DS, Ruan WJ, Saha TD, et al. Prevalence, correlates and comorbidity of nonmedical prescription drug use and drug use disorders in the United States: Results of the national epidemiologic survey on alcohol and related conditions. J Clin Psychiatry. 2006 Jul;67(7):1062-73. [PubMed]
8. Simonsen KW, Christoffersen DJ, Banner J, Linnet K, Andersen LV. Fatal poisoning among patients with drug addiction. Dan Med J. 2015 Oct;62(10):A5147. [PubMed]
9. Sporer KA, Dorn E. Heroin-related noncardiogenic pulmonary edema: a case series. Chest. 2001 Nov;120(5):1628-32. [PubMed]
10. Centers for Disease Control and Prevention (CDC). Atypical reactions associated with heroin use-five states, January-April 2005. MMWR Morb Mortal Wkly Rep. 2005 Aug 19; 54(32):793-6. [PubMed]
11. Bryant WK, Galea S, Tracy M, Markham T, Tardiff KJ, Vlahov D. Overdose deaths attributed to methadone and heroin in New York City, 1990-1998. Addiction. 2004 Jul;99(7):846-54. [PubMed]
12. Rudd RA, Paulozzi LJ, Bauer MJ, Burleson RW, Carlson RE, Dao D, et al. Increases in heroin overdose deaths – 28 states, 2010-2012. MMWR Morb Mortal Wkly Rep. 2014 Oct 3;63(39):849-854. [PubMed].

Received: 14 September 2016
Published online: 25 January 2017

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