Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2013, vol. 19, book 4
Subject Collection: Oral and Dental Medicine
Pages: 422-425
DOI: 10.5272/jimab.2013194.422
Published online: 12 December 2013

J of IMAB 2013 Jul-Dec;19(4):422-425
Assya Krasteva 1Corresponding Autor, Angelina Kisselova1, Vessela Dineva1, Aneta Ivanova2, Zahariy Krastev2.
1) Department of Oral Imaging and Oral Diagnostic, Faculty of Dental Medicine,
2) Clinic of Gastroenterology, University Hospital "St.Ivan Rilski",
Medical University Sofia, Bulgaria.

Actually the burning mouth syndrome (BMS) can be classified as idiopathic and secondary. The deficiency of vitamins (especially the group B) can be involved in BMS. In a group of 92 consecutive Bulgarian patients without oral lesions, excessive gingivitis and parodontitis or abscess, 63 patients had lower level of folic acid in serum (68%). The serum levels of vitamin B12 were lower in 17,5% and microbes were found in 10%. The study revealed that the most frequent abnormality in Bulgarian BMS patients was the folate deficiency followed by the lower level of cobalamin and oral candidiasis. These high rates of deficiency suggest a long term folic acid supplementation.

Key words: burning mouth; folic acid; vitamin B12;

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Please cite this article as:
Krasteva A, Kisselova A, Dineva V, Ivanova A, Krastev Z. Folic acid and vitamin B12 levels in Bulgarian patients with burning mouth syndrome. J of IMAB. 2013 Jul-Dec;19(4):422-425. doi: 10.5272/jimab.2013194.422.

Correspondence to: Dr. Assya Krasteva, Department of Oral Imaging and Oral Diagnostic, Faculty of Dental Medicine, Medical University Sofia; 1, St George Sofiisky str., 1431 Sofia, Bulgaria;,

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Received: 08 October 2013
Published online: 12 December 2013

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