Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2013, vol. 19, book 4
Subject Collection: Oral and Dental Medicine
Pages: 371-373
DOI: 10.5272/jimab.2013194.371
Published online: 19 September 2013

J of IMAB 2013; 19(4):371-373
Miglena Balcheva 1Corresponding Autor, Angelina Kisselova-Yaneva2.
1) Faculty of Dental Medicine, Medical University, Varna, Bulgaria.
2) Department of Oral Imaging and Oral Diagnostic, Faculty of Dental Medicine, Medical University Sofia, Bulgaria.

Food allergy and intolerance are wide spread nowadays. However, the problem existed and was registered and described still by the ancients. It was fully understood and scientifically depicted in the 20th century after IgE and anaphylaxis were discovered, new diagnostic tests were initiated and the term “allergy” was introduced. There are some interesting aspects of the problem. Epidemiology is the first one – in the last two decades the number of people suffering from food allergy increased significantly and reached 4% of the population. Food allergy covers all ages, both sexes; atopic people and these with other allergic or digestive diseases are in the risk group also. There is certain influence of the eating habits as well. Etiology is rich and varied. It includes all foodstuffs of plant and animal origin, spices, honey, medicinal products - milk, eggs, meat, fish, nuts, fruits and vegetables, etc. Pathogenesis is complex.

Key words: food allergy, oral allergy syndrome, hypersensitivity.

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Please cite this article as:
Balcheva M, Kisselova-Yaneva A. Food allergy and oral allergy syndrome. Part I. A review. J of IMAB. 2013; 19(4):371-373. doi: 10.5272/jimab.2013194.371.

Correspondence to: Dr Miglena Balcheva, Faculty of Dental Medicine, Medical University - Varna; 84, Tzar Osvoboditel Boul., office 623; 9002-Varna, Bulgaria; E-mail:;

1. Johansson SG, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T. et al. A revised nomenclature for allergy. An EAACI position statement for the EAACI nomenclatute task force. Allergy. 2001 Sep;56(9)813-24. [PubMed] [CrossRef]
2. Simpson HA. Adverse reactions to food. In: Allergy – principles and practice. Ed. by Middleton E, Mosby, St. Louis, 2003, 1619-1643
3. Petrunov B, Dimitrov V, Kisselova-Yaneva A. – Clinical immunology. Clinical allergology. Dental clinical allergology. ARSO Medical Publisher, 2009 [in Bulgarian]
4. Rancé F, Dutau G. Food allergy. Expansion Formation et Editions, Paris, France, 2008.
5. Sicherer SH, Sampson HA. Food allergy: recent advances in pathophysiology and treatment. Annu Rev Med. 2009 Feb;60:261-77. [PuMed] [CrossRef]
6. Kagan RS. Food allergy: an overview. Environ Health Perspect. 2003 Feb;111(2):223-225. [PubMed]
7. Mileva Zh. Frequency of allergic diseases in Bulgaria. Allergy&Asthma. 2000; 5(Supl. 1):3-32 [in Bulgarian]
8. Hill DJ, Hosking CS, Heine RG. Clinical spectrum of food allergy in children in Australia and South-East Asia: identification and targets for treatment. Ann Med. 1999 Aug;31(4):272-81. [PubMed]
9. Crespo JF, Pascual C, Burks AW, Helm RM, Esteban MM. – Frequency of food allergy in a pediatric population from Spain. Pediatr Allergy Immunol. 1995 Feb;6(1):39-43. [PubMed]
10. Kivity S, Dunner K, Marian Y. The pattern of food hypersensitivity in patients with onset after 10 years of age. Clin Exp Allergy. 1994 Jan;24(1)19-22. [PubMed]
11. Pascual CY, Fernandez-Crespo J, Sanchez Pastor S, Ayuso R, Garcia Sanchez G, Martin-Esteban M. Allergy to lentils in Spain. Pediatr Pulmonol. 2001, Suppl 23, 41-3. [PubMed]
12. Goh DL, Lau YN, Chew FT, Shek LP, Lee BW. Pattern of food-induced anaphylaxis in children of an Asian community. Allergy. 1999 Jan;54(1):84-6. [PubMed] [CrossRef]
13. Chatchatee P, Jarvinen KM, Bardina L, Vila L, Beyer K, Sampson HA. Identification of IgE- and IgG-binding epitopes on b- and k-casein in cow’s milk allergic patients. Clin Exp Allergy. 2001 Aug;31(8):1256-62. [PubMed] [CrossRef]
14. Sampson HA. Update on food allergy. J Allergy Clin Immunol. 2004 May;113(5):805-19. [PubMed] [CrossRef] .

Received: 02 July 2013
Published online: 19 September 2013

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