back to 2013, vol. 19, b. 1
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2013, vol. 19, book 1;
Subject Collection: Medicine
Page: 379-381
DOI: 10.5272/jimab.2013191.379
Published online: 1 February 2013

J of IMAB. 2013; 19(1):379-381;
Miroslav Marinov1, Iglika Marinova2, Kosta Mirchev3, Borislav Boychev4, Christiana Romanova2, Nina Radeva5, Radko Zl. Radev 1Corresponding Autor
1) Department of Preclinical and Clinical Sciences, 2) Department of Hygiene and disaster medicine, 3) Department of Physiology and Pathophysiology, 4) University Hospital – Varna, 5) Department of Health Management,
Medical University – Varna, Bulgaria.

The authors examine the dependence between reaction time as an indicator of change at cerebral level and H-reflex amplitude change being a relative index of excitability level in the spinal cord during the preparation of a simple voluntary movement in thyrotoxicosis patients. Electrophysiological investigations are carried out after identifying the disease and prior to the beginning of causal therapy. Patients are comfortably seated on a chair in a dark room and respond to light signal from a blitz-lamp and it was determined reaction time. Simultaneously with light signal presentation, nervus tibialis in the popliteal fossa of the same leg is excited to evoke H-reflex. One-day signal programme consists of a total of 120 light signals divided into three equal blocks. H-reflex amplitude evoked only once for every light signal is compared with control H-reflex amplitude. Its decrease or increase is read. Reaction times are grouped according to the extern of corresponding H-reflex amplitude increase or decrease. Data obtained serve to construct relation curve between reaction time and H-reflex amplitude changes. This relation curve differs in nature from the curve when healthy subjects under the same experimental conditions are tested.

Key words: reaction time, H-reflex amplitude change, thyrotoxicosis, voluntary movement.

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Please cite this article as:
Marinov M, Marinova I, Mirchev K, Boychev B, Romanova Ch, Radeva N, Radev RZ. Relationship between reaction time and amplitude changes of the H-reflex in the performance of simple motor task in patients with thyrotoxicosis. J of IMAB. 2013; 19(1):379-381. DOI: 10.5272/jimab.2013191.379.

Correspondence to: Radko Zlatkov Radev, MD, PhD. Department of preclinical and clinical medicine, Medical University of Varna, Bulgaria.

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Accepted for publication: 17 June 2012
Published online: 1 February 2013

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