|
Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X (Online)
Issue: 2012, vol. 18, book 4
Subject Collection: Oral and Dental Medicine
Pages: 255-262
DOI: 10.5272/jimab.2012184.255
Published online: 23 October 2012
J of IMAB 2012; 18(4):255-262
ALLERGIC CONTACT DERMATITIS FROM FORMALDEHYDE EXPOSURE.
Maya Lyapina1, Angelina Kisselova-Yaneva2, Assya Krasteva2, Mariana Tzekova–Yaneva2, Maria Dencheva-Garova2
1) Department of Hygiene, Medical Ecology and Nutrition, Medical Faculty,
2) Department of Oral and Image Diagnostic, Faculty of Dental Medicine,
Medical University, Sofia, Bulgaria.
ABSTRACT:
Formaldehyde is a ubiquitous chemical agent, a part of our outdoor and indoor working and residential environment. Healthcare workers in difficult occupations are among the most affected by formaldehyde exposure. Formaldehyde is an ingredient of some dental materials. Formaldehyde is well-known mucous membrane irritant and a primary skin sensitizing agent associated with both contact dermatitis (Type IV allergy), and immediate, anaphylactic reactions (Type I allergy). Inhalation exposure to formaldehyde was identified as a potential cause of asthma. Quite a few investigations are available concerning health issues for dental students following formaldehyde exposure. Such studies would be beneficial for early diagnosis of hypersensitivity, adequate prophylactic, risk assessment and management of their work.
Key words: formaldehyde, allergic contact dermatitis, occupational exposure, dental materials, healthcare workers.
- Download FULL TEXT /PDF 698 KB/
Please cite this article as: Lyapina M, Kisselova-Yaneva A, Krasteva A, Tzekova–Yaneva M, Dencheva-Garova M. ALLERGIC CONTACT DERMATITIS FROM FORMALDEHYDE EXPOSURE. J of IMAB. 2012; 18(4):255-262. doi: 10.5272/ jimab.2012184.255.
REFERENCES:
1 М. Nosko, Е. Petrova, М. Lyapin, N. Madjunov, Т. Panev, B. Dragova, St. Lalchev. Occupational risk in formaldehyde exposure. ProblemsofHygiene. 2000, XXI, №1, 16-21. [in Bulgarian]
2. М. Nosko, Е. Petrova, М. Lyapin, B. Dragova, М. Boev, J. Pomakov, G. Zelezova. Toxic actions of occupational formaldehyde exposure. Hygiene and Public Health. 2001 2-3, 40-44. [in Bulgarian]
3. М. Nosko, Е. Petrova, М. Lyapin, D. Baltadjieva, N. Madjunov, Chr. Christov, М. Stoynovska. Investigation of some aspects of the immunotoxic action of formaldehyde. Hygiene and Public Health. 1999, 2, 16-18. [in Bulgarian]
4. Aalto-Korte K, Kuuliala O, Suuronen K, Alamko K. Occupational contact allergy to formaldehyde and formaldehyde releasers. Contact Dermatitis. 2008 Nov;59(5):280-9. [PubMed] [CrossRef]
5. Aalto-Korte K, Mäkelä EA, Huttunen M, Suuronen K, Jolanki R. Occupational contact allergy to glyoxal. Contact Dermatitis. 2005 May;52(5):276-81. [PubMed] [CrossRef]
6. Andersen I., Mølhave L. (1983) Controlled human studies with formaldehyde. In: Gibson, JE; ed. Formaldehyde toxicity. Washington, DC: Hemisphere Publishing Corporation; pp. 154–165
7. Ballarin C, Sarto F, Giacomelli L. Bartolucci GB, Clonfero E. Micronucleated cells in nasal mucosa of formaldehyde-exposed workers. Mutat Res. 1992 Jul;280(1):1-7. [PubMed]
8. Bateson T.F., Schwartz J. Children's response to air pollutants. J Toxicol Environ Health A. 2008, 71(3):238-243. [PubMed] [CrossRef]
9. Bell HK, King CM. Allergic contact dermatitis from urea-formaldehyde resin in medium-density fibreboard (MDF). Contact Dermatitis. 2002 Apr;46(4):247. [PubMed] [CrossRef]
10. Bernstein RS, Stayner LT, Elliott LJ. Kimbrough R, Falk H, Blade L. Inhalation exposure to formaldehyde: an overview of its toxicology, epidemiology, monitoring, and control. Am Ind Hyg Assoc J. 1984 Nov;45(11):778-85. [PubMed]
11. Bostrom CE, Almen J, Steen B. Westerholm R. Human exposure to urban air pollution. Environ Health Perspect. 1994 Oct;102, Soppl 4:39-47. [PubMed]
12. Boysen M, Zadig E, Digernes V, Abeler V, Reith A. Nasal mucosa in workers exposed to formaldehyde: a pilot study. Br J Ind Med. 1990 Feb;47(2):116–121. [PubMed]
13. Braun JJ, Valfrey J, Scherer P, Zana H, Haikel Y, Pauli G. IgE allergy due to formaldehyde paste during endodontic treatment. Apropos of 4 cases: 2 with anaphylactic shock and 2 with generalized urticaria. Rev Stomatol Chir Maxillofac. 2000 Oct;101(4):169-74. [Article in French] [PubMed]
14. Braun JJ, Zana H, Purohit A, Valfrey J, Scherer P, Haïkel Y, et al. Anaphylactic reactions to formaldehyde in root canal sealant after endodontic treatment: four cases of anaphylactic shock and three of generalized urticaria. Allergy. 2003 Nov;58(11):1210-5. [PubMed]
15. Broder I, Corey P, Brasher P, Lipa M, Cole P. Formaldehyde exposure and health status in households. Environ Health Perspect. 1991 Nov;95:101-104. [PubMed]
16. Casanova M, Heck HD, Everitt JI, Harrington WW Jr, Popp JA. Formaldehyde concentrations in the blood of rhesus monkeys after inhalation exposure. Food Chem Toxicol. 1988 Aug;26(8):715-716. [PubMed]
17. Casset A., Purohit A., Marchand C. Le Calvé S, Donnay C, Uring-Lambert B, et al. The bronchial response to inhaled formaldehyde. Rev Mal Respir. 2006 Feb;23(1 Suppl):3S25–34. [Article in French] [PubMed]
18. Final Report on Formaldehyde Levels in FEMA-Supplied Travel Trailers, Park Models and Mobile Homes. Centers for Disease Control and Prevention (U.S.). CDC (2008)
19. Cockayne SE, McDonagh AJ, Gawkrodger DJ. Occupational allergic contact dermatitis from formaldehyde resin in clothing. Contact Dermatitis. 2001 Feb;44(2):109–110. [PubMed] [CrossRef]
20. Cohen BI, Pagnillo MK, Musikant BL, Deutsch AS. Evaluationof the release of formaldehyde for three endodontic filling materials. Oral Health. 1998 Dec;88(12):37-9. [PubMed]
20. Costantini C, Cassatella М. Crosstalks between neutrophils and NK cells. J Leukoc Biol. 2011 Feb;89(2):221-233. [PubMed]
21. Crump DR. 1995. Volatile organic compounds in indoor air. In: Hester RE, Harrison RM, ed. Volatile organic compounds in the atmosphere. Issues in environmental science and technology 4th ed. Cambridge: Royal Society of Chemistry, 109-124.
22. Dally KA, Hanrahan LP, Woodbury MA, Kanarek MS. Formaldehyde exposure in nonoccupational environments. Arch Environ Health. 1981 Nov-Dec;36(6):277-284. [PubMed]
23. De Groot AC, Le Coz CJ, Lensen GJ, Flyvholm MA, Maibach HI, Coenraads PJ. Formaldehyde-releasers: relationship to formaldehyde contact allergy. Part 2. Formaldehyde-releasers in clothes: durable press chemical finishes. Contact Dermatitis. 2010 Jul;63(1):1-9. [PubMed] [CrossRef]
24. Delfino RJ. Epidemiologic evidence for asthma and exposure to air toxics: linkages between occupational, indoor, and community air pollution research. Environ Health Perspect. 2002 Aug;110 Suppl 4:573–589. [PubMed]
25. Delfino RJ, Gong H Jr, Linn WS, Pellizzari ED, Hu Y. (2003) Asthma symptoms in Hispanic children and daily ambient exposures to toxic and criteria air pollutants. Environ Health Perspect. 2003 Apr;111(4):647–656. [PubMed]
26. Doi S, Suzuki S, Morishita M, Yamada M, Kanda Y, Torii S, et al. The prevalence of IgE sensitization to formaldehyde in asthmatic children. Allergy. 2003 Jul;58(7):668–671. [PubMed] [CrossRef]
27. Doty RL, Cometto-Muniz JE, Jalowayski AA, Dalton P, Kendal-Reed M, Hodgson M. Assessment of upper respiratory tract and ocular irritative effects of volatile chemicals in humans. Crit Rev Toxicol. 2004 Mar-Apr;34(2):85–142. [PubMed]
28. el Sayed F, Seite-Bellezza D, Sans B, Bayle-Lebey P, Marguery MC, Bazex J. (1995) Contact urticaria from formaldehyde in a root-canal dental paste. Contact Dermatitis. 1995 Nov;33(5):353. [PubMed]
29. Ezughah FI, Murdoch SR, Finch TM. Occupational airborne allergic contact dermatitis from medium-density fibreboard containing phenol-formaldehyde resin-2 (PFR-2). Contact Dermatitis. 2001 Oct;45(4):242. [PubMed] [CrossRef]
30. Fehr B, Huwyler T, Wuthrich B. Formaldehyde and paraformaldehyde allergy. Allergic reactions to formaldehyde and paraformaldehyde after tooth root treatments. [Article in French, German] Schweiz Monatsschr Zahnmed. 1992 102(1):94-7. [PubMed]
31. Feron VJ. Til HP, de Vrijer F, Woutersen RA, Cassee FR, van Bladeren PJ. Aldehydes: occurrence, carcinogenic potential mechanism of action and risk assessment. Mutat Res. 1991 Mar-Apr;259(3-4):363-385. [PubMed]
32. Finch TM, Prais L, Foulds IS. Allergic contact dermatitis from medium-density fibreboard containing melamine-formaldehyde resin. Contact Dermatitis. 1999 Nov;41(5):291. [PubMed]
33. Flyvholm MA. Contact allergens in registered chemical products. Contact Dermatitis. 1991 Jul;25(1):49-56. [PubMed]
34. Garcнa Bracamonte B, Ortiz de Frutos FJ, Iglesias Diez L. Occupational allergic contact dermatitis due to formaldehyde and textile finish resins. Contact Dermatitis. 1995 Aug;33(2):139-40. [PubMed]
35. Garcia JP, Beyne-Masclet S, Mouvier G. Emissions of volatile organic compounds by coal-fired power stations. Atmos Environ. 1992; 26A(9):1589-1597.
36. Gawkrodger DJ. Investigation of reactions to dental materials. Br J Dermatol. 2005 Sep;153(3):479-85. [PubMed] [CrossRef]
37. Garry VF, Oatman L, Pleus R. Gray D. Formaldehyde in the home: Some environmental disease perspectives. Minn Med. 1980 Feb;63(2):107-111. [PubMed]
38. Geier J, Lessmann H, Becker D, Bruze M, Frosch PJ, Fuchs T, et al. Patch testing with components of water-based metalworking fluids: results of a multicentre study with a second series. Contact Dermatitis. 2006 Dec;55(6):322-9. [PubMed] [CrossRef]
39. Hauman CH, Love RM. Biocompatibility of dental materials used in contemporary endodontic therapy: a review. Part 2. Root-canal-filling materials. Int Endod J. 2003 Mar;36(3):147-160. [PubMed] [CrossRef]
40. Heck HD, Casanova-Schmitz M, Dodd PB, Schachter EN, Witek TJ, Tosun T. Formaldehyde (CH2O) concentrations in the blood of humans and Fischer-344 rats exposed to CH2O under controlled conditions. Am Ind Hyg Assoc J. 1985 Jan;46(1):1-3. [PubMed]
41. Holmstrom M, Wilhelmsson B. Respiratory symptoms and pathophysiological effects of occupational exposure to formaldehyde and wood dust. Scand J Work Environ Health. 1988 Oct;14(5):306-311. [PubMed] [CrossRef]
42. Holness DL, Nethercott JR. Health status of funeral service workers exposed to formaldehyde. Arch Environ Health. 1989 Jul-Aug;44(4):222-8. [PubMed]
43. HSDB. 2009. Hazardous Substances Data Bank. National Library of Medicine. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB and search on CAS number. Last accessed: 6/2/09.
44. IARC. (2006) Formaldehyde. In IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Formaldehyde, 2-Butoxyethanol and 1-tert-Butoxypropan-2-ol, vol. 88, Lyon, France: International Agency for Research on Cancer. pp. 39-325
45. Kiec-Swierczynska M, Krecisz B. Causes of occupational allergy in dental nurses. An analysis based on the material collected at The Institute of Occupational Medicine in Lódź. Med Pr. 2000, 51(2):145-9. [Article in Polish] [PubMed]
46. Kieć-Swierczyńska M.Contact allergy caused by formaldehyde, based on materials from the Institute for medical occupations in Lodz. Med Pr. 1993, 44(3):209-13. [Article in Polish][PubMed]
47. Kiec-Swierczynska M.Occupational allergic contact dermatitis in Lodz: 1990-1994. OccupMed (Lond). 1996, Jun;46(3):205-208. [PubMed]
48. Kieć-Swierczyńska M, Krecisz B. Occupational skin diseases among the nurses in the region of Lódź. Int J Occup Med Environ Health. 2000, 13(3):179-84. [PubMed]
49. Kieć-Swierczyńska M, Krecisz B, Krysiak B. Kuchowicz E, Rydzyński K. Occupational allergy to aldehydes in health care workers. Clinical observations. Experiments. Int J Occup Med Environ Health. 1998; 11(4):349-58. [PubMed]
50. Kieć-Swierczyńska M, Krecisz B, Swierczyńska-Machura D. Most frequent causes of allergic contact dermatitis in farmers: based on material collected in the Nofer Institute of Occupational Medicine, Lodz. [Article in Polish] Med Pr. 2003; 54(3):237-43. [PubMed]
51. Kijima A, Nishino H, Umeda J, Kataoka Y. Type 1 allergy to formaldehyde in root canal sealant after dental treatment: two case reports and review of the literature. [Article in Japanese] Arerugi. 2007 Nov;56(11):1397-402. [PubMed]
52. Koch MJ. Formaldehyde release from root-canal sealers: influence of method. Int Endod J. 1999 Jan;32(1):10-6. [PubMed] [CrossRef]
53. Koch P. Occupational contact dermatitis from colophony and formaldehyde in banknote paper. Contact Dermatitis. 1995 Jun;32(6):371–372. [PubMed]
54. Krecisz B, Kieć-Swierczyńska M. The role of formaldehyde in the occurrence of contact allergy. [Article in Polish] Med Pr. 1998 49(6):609-14. [PubMed]
55. Krzyzanowski M, Quackenboss JJ, Lebowitz MD. Chronic respiratory effects of indoor formaldehyde exposure. Environ Res. 1990 Aug;52(2):117–125. [PubMed]
56. Lang I, Bruckner T, Triebig G. Formaldehyde and chemosensory irritation in humans: A controlled human exposure study. Regul Toxicol Pharmacol. 2008 Feb;50(1):23–36. [PubMed] [CrossRef]
57. Liskowsky J, Geier J, Bauer A. Contact allergy in the cleaning industry: analysis of contact allergy surveillance data of the Information Network of Departments of Dermatology. Contact Dermatitis. 2011 Sep;65(3):159-166. [PubMed] [CrossRef]
58. Liu KS, Huang FY, Hayward SB, Wesolowski J, Sexton K. Irritant effects of formaldehyde exposure in mobile homes. Environ Health Perspect. 1991 Aug;94:91–94. [PubMed]
59. Lyapina M, Zhelezova G, Petrova E, Boev M. Flow cytometric determination of neutrophil respiratory burst activity in workers exposed to formaldehyde. Int Arch Occup Environ Health. 2004 Jun;77(5):335-340. Epub 2004 May 1. [PubMed] [CrossRef]
60. Maibach H. Formaldehyde: effects on animal and human skin. In: Gibson J.E., ed. Formaldehyde toxicity. Washington, DC: Hemisphere Publishing Corporation. 1983 166-174.
61. Marks JGJ, Belsito DV, DeLeo VA. et al. (1995) North American contact dermatitis group standard tray patch test results (1992 to 1994). Am J Contact Dermatitis 6:160-165
62. Nedorost S, Warshaw E, Jacob S, Katta R, Zirwas M, Andrew S. Allergic contact dermatitis caused by durable-press finishes does exist in the USA. Contact Dermatitis. 2010 Oct;63(4):233-4. [PubMed] [CrossRef]
63. NTP (2010) Report on Carcinogens Background Document for Formaldehyde. National Toxicology Program. http://ntp.niehs.nih.gov/ntp/roc/twelfth/2009/November/Formaldehyde_BD_Final.pdf .
64. Ohmichi K, Komiyama M, Matsuno Y, Sawabe Y, Miyaso H, Fukata H, et al. Relationship between exposure to formaldehyde and immunoglobulin E (IgE) production during the gross anatomy laboratory. J Health Sci. 2006; 52(5):642–647.
65. Owen CM, Beck MH. Occupational allergic contact dermatitis from phenol-formaldehyde resins. Contact Dermatitis. 2001 Nov;45(5):294–295. [PubMed] [CrossRef]
66. Pazdrak K, Gуrski P, Krakowiak A, Ruta U. Changes in nasal lavage fluid due to formaldehyde inhalation. Int Arch Occup Environ Health. 1993; 64(7):515–519. [PubMed]
67. Rastogi SC. A survey of formaldehyde in shampoos and skin creams on the Danish market. Contact Dermatitis. 1992 Oct;27(4):235-240. [PubMed]
68. Ravis SM, Shaffer MP, Shaffer CL, Dehkhaghani S, Belsito DV. Glutaraldehyde-induced and formaldehyde-induced allergic contact dermatitis among dental hygienists and assistants. J Am Dent Assoc. 2003 Aug;134(8):1072-1078. [PubMed]
69. Reich HC, Warshaw EM. Allergic contact dermatitis from formaldehyde textile resins. Dermatitis. 2010 Apr;21(2):65-76. [PubMed]
70. Ross JS, Rycroft RJ, Cronin E. Melamine-formaldehyde contact dermatitis in orthopaedic practice. Contact Dermatitis. 1992 Mar;26(3):203–204. [PubMed]
71. Salthammer Т, Mentese S, Marutzky R. Formaldehyde in the Indoor Environment. Chem Rev. 2010 Apr 14;110(4):2536–2572. [PubMed] [CrossRef]
72. Sanchez I, Rodriguez F, Quiсones D, Garcia-Abujeta JL, Fernandez L, Martin-Gil D. Occupational dermatitis due to formaldehyde in newspaper. Contact Dermatitis. 1997 Sep;37(3):131–132. [PubMed]
73. Schnuch A, Uter W, Geier J, Frosch PJ, Rustemeyer T. Contact allergies in healthcare workers. Results from the IVDK. Acta Derm Venerol. 1998 Sep;78(5):358-363. [PubMed]
74. Shaffer MP, Belsito DV. Allergic contact dermatitis from glutaraldehyde in health-care workers. Contact Dermatitis. 2000 Sep;43(3);150-6. [PubMed] [CrossRef]
75. Slodownik D, Williams J, Tate B, Tam M, Cahill J, Frowen K, et al. Textile allergy - the Melbourne experience. Contact Dermatitis. 2011 Jul;65(1):38-42. [PubMed] [CrossRef]
76. Suuronen K, Aalto-Korte K, Piipari R, Tuomi T, Jolanki R. Occupational dermatitis and allergic respiratory diseases in Finnish metalworking machinists. Occup Med (Lond). 2007 Jun;57(4):277-83. [PubMed] [CrossRef]
77. Takahashi S, Tsuji K, Fujii K, Okazaki F, Takigawa T, Ohtsuka A, et al. Prospective study of clinical symptoms and skin test reactions in medical students exposed to formaldehyde gas. J Dermatol. 2007 May;34(5):283–289. [PubMed] [CrossRef]
78. Takigawa T, Usami M, Yamasaki Y, Wang B, Sakano N, Horike T, et al. Reduction of indoor formaldehyde concentrations and subjective symptoms in a gross anatomy laboratory. Bull Environ Contam Toxicol. 2005 Jun;74(6):1027–1033. [PubMed]
79. Tang X, Bai Y, Duong A, Smith MT, Li L, Zhang L. Formaldehyde in China: Production, consumption, exposure levels, and health effects. Environ Int. 2009 Nov;35(8):1210-1224. [PubMed] [CrossRef]
80. Tas E, Pletscher M, Bircher AJ. IgE-mediated urticaria from formaldehyde in a dental root canal compound. J Investig Allergol Clin Immunol. 2002; 12(2):130-3. [PubMed]
81. U.S. Department of Health and Human Services, Public Health Service, National Toxicology Program. (2011) Report on Carcinogens, Twelfth Edition; http://ntp.niehs.nih.gov/ntp/roc/twelfth/roc12.pdf
82. White JML, White IR, de Groot AC. Cosmetics and Skin Care Products. Contact Dermatitis, 2011; 6, 591-605. [CrossRef]
83. WHO (2002) Formaldehyde: Concise International Chemical Assessment Document World Health Organization. Geneva. http://www.inchem.org/documents/cicads/cicads/cicad40.htm
84. Wilhelmsson B, Holmström M. Possible mechanisms of formaldehyde-induced discomfort in the upper airways. Scand J Work Environ Health. 1992 Dec;18(6):403–407. [PubMed] [CrossRef]
85. Zina AM, Fanan E, Bundino S. Allergic contact dermatitis from formaldehyde and quaternium-15 in photocopier toner. Contact Dermatitis. 2000 Oct;43(4):241-2. [PubMed].
Accepted for publication: 16 August 2012
Issue published online: 23 October 2012
back to Online Journal |