Journal of IMAB - Annual Proceeding (Scientific Papers)
, Gospodin Iliev
ISSN: 1312 773X
Issue: 2007, vol. 13, book 1
Subject Collection: Medicine
Online date: September 10, 2007
J of IMAB 2007; 13(1):31-34
SERUM ELECTROLYTES IN LEPTOSPIROSIS
Galya I. Gancheva, Maria Atanasova, Penka Ilieva,
Department of Infectious Diseases, Epidemiology, Parasitology and Tropical Medicine; Medical University, Pleven, Bulgaria
Serum levels of electrolytes (sodium, chlore, potassium and ionized calcium) in ninety four cases of leptospirosis have been investigated dynamically with routine laboratory methods. Twenty six cases had been with mild course (27,66%), thirty eight with moderate (40,43%), and thirty with severe leptospirosis (31,91%) (р>0,1). The comparison of different serum levels (decreased, normal and increased) of the electrolytes and their averages have revealed significantly increasing only of sodium average before discharge (p<0,05). Analysis of the percentage of cases with different serum levels (normal, below and above normal) of electrolytes in different severity of the disease has been found significantly higher occurrence of hyponatriemia in moderate and severe leptospirosis (p<0,05). Decreased serum levels of ionized calcium have been established in thirteen cases, twelve of them with severe leptospirosis (p<0,05). The dynamical control on the serum levels of sodium, chlore, and potassium have not revealed significant differences in percentage of the disorders (p>0,05). Marked prevalence of the cases with decreased ionized calcium during the hospital period has been observed (p<0,02). In conclusion: electrolytic disorders have not been significant for diagnosis of leptospirosis because they have been observed in ARF independent of the etiology but they have been important for evaluation of the severity and correct treatment of the disease.
Key words: leptospirosis, acute renal failure, serum electrolytes, sodium, chlore, potassium, ionized calcium.
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Gancheva GI, Atanasova M, Ilieva P. SERUM ELECTROLYTES IN LEPTOSPIROSIS. J of IMAB. 2007; 13(1):31-34. doi: 10.5272/jimab.2007131.29
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