Journal of IMAB - Annual Proceeding (Scientific Papers)
Publisher: Peytchinski, Gospodin Iliev
ISSN: 1312 773X
Issue: 2016, vol. 22, issue 2
Subject Area: Medicine
Published online: 31 May 2016
J of IMAB 2016 Apr-Jun;22(2):1132-1135
PEDIATRIC URINARY INFECTIONS, CAUSED BY EXTENDED-SPECTRUM BETA-LACTAMASE - PRODUCING MICROORGANISMS IN VARNA, BULGARIA
Neli M. Ermenlieva1 , Dimitrichka D. Bliznakova2, Gabriela S. Tsankova1, Tsvetelina K. Popova2, Emiliq P. Georgieva2, Tatina T. Todorova2.
1) Department of Preclinical and Clinical Sciences, Faculty of Pharmacy, Medical University - Varna, Bulgaria.
2) Medical College, Medical University - Varna, Bulgaria.
Background: Extended-spectrum beta-lactamase (ESBLs) producing bacteria are microorganisms which have the ability to hydrolyze β-lactame ring of a large part of the antibiotics, commonly used to treat bacterial infections including urinary tract infections.
Purpose: The aim of this study is present the epidemiology of childhood urinary tract infections caused by ESBL-producing strains in Varna, Bulgaria.
Material/methods: A total of 3895 urine samples of children patients (aged 0 to 18 years) were examined during the period 2010-2012 for presence of ESBL-producing bacteria.
Results: Six percent of the tested urinary samples were positive for ESBL production. All of the isolates were resistant to ampicillin, piperacillin, cephalothin, cefprozil, cefuroxime, ceftriaxone, ceftazidime, levofloxacin, cefaclor, but were were sensitive to meropenem and imipenem.
Conclusions: Cephalosporins and penicillins are the most used antibiotics in Bulgaria, but they should be very precisely prescribed in medical practice, because otherwise preconditions for maintaining high share of ESBLs are created.
Key words: Extended-spectrum beta-lactamase producing bacteria, urinary tract infections, pediatric infections, antibiotic resistance,
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Please cite this article in PubMed Style or AMA (American Medical Association) Style:
Ermenlieva NM, Bliznakova DD, Tsankova GS, Popova TK, Georgieva EP, Todorova TT. PEDIATRIC URINARY INFECTIONS, CAUSED BY EXTENDED-SPECTRUM BETA-LACTAMASE - PRODUCING MICROORGANISMS IN VARNA, BULGARIA. J of IMAB. 2016 Apr-Jun;22(2):1132-1135. DOI: http://dx.doi.org/10.5272/jimab.2016222.1132.
Correspondence to: Neli Mitkova Ermenlieva, Department of Preclinical and Clinical Sciences, Faculty of Pharmacy, Medical University-Varna; 55, Marin Drinov Str., 9002 Varna, Bulgaria; E-mail: Neli.Ermenlieva@mu-varna.bg
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Received: 09 March 2016
Published online: 31 May 2016
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